PARENTAL LABORATORY FINDINGS OF PATIENTS WITH HOMOZYGOUS THALASSEMIA REFERRED TO IMMAM HOSSEIN HOSPITAL(1998)

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EHTERAM H.; SHAFAGHI B.

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Journal: Feyz Medical Sciences Journal Year:2000 | Volume:4 | Issue:13 Page(s): 81-88

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Title

PARENTAL LABORATORY FINDINGS OF PATIENTS WITH HOMOZYGOUS THALASSEMIA REFERRED TO IMMAM HOSSEIN HOSPITAL(1998)

Author(s)

EHTERAM H. | SHAFAGHI B. | Issue Writer Certificate

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Abstract

History and Objectives: Due to the prevalence of the beta-thalassemia carriership in our country, and the emphasis on the controlling and prophylaxis of the chronic symptoms, we decieded to review complete blood count (CBe) and hemoglobin electrophoresis among parents of major beta thalassemic patients that were referred to the Immam Hossein Hospital in 1997-1998. Materials and Methods: A descriptive study concerning parents of all beta-thalassemic patients that are referred to the Imam Hossein Hospital was carried out. Blood samples were taken for CBC and electrophoretic analysis. MCV and MCH levies of lower than 80fL and 27pg respectively were considered abnormal. HbA2levels higher than 3.5% was also considered as abnormal. Results: All 48 candidates (100%) had reduced MCV and MCR. MCV and MCH were 60I45fL and 20I1.5pg respectively. 62.5% had increased and 37.5% had normal RBC count. No record of low RBC was encountered. Results of electrophoretic test were as follows: HbF 2.4 I 2.4% and HbA2 5.2I1.1%. 89.5% of individuals had abnormal electrophoretic results and 10.5% had normal HbA2 levels (lower than 3.5%). Conclusions: All parents of beta-thalessemic major patients had abnormality in their CBC index, therefore the first step in evaluation of beta-thalassemia ought to be CBC assessment and once abnormal results are reported then electrophoretic analysis should be carried out. Further study on the diagnostic efficiency of CBC index in detection of minor beta-thalassemia is recommended.

Cites

STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002)

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APA: Copy

EHTERAM, H., & SHAFAGHI, B.. (2000). PARENTAL LABORATORY FINDINGS OF PATIENTS WITH HOMOZYGOUS THALASSEMIA REFERRED TO IMMAM HOSSEIN HOSPITAL(1998) . FEYZ, 4(13), 81-88. SID. https://sid.ir/paper/370758/en

Vancouver: Copy

EHTERAM H., SHAFAGHI B.. PARENTAL LABORATORY FINDINGS OF PATIENTS WITH HOMOZYGOUS THALASSEMIA REFERRED TO IMMAM HOSSEIN HOSPITAL(1998) . FEYZ[Internet]. 2000;4(13):81-88. Available from: https://sid.ir/paper/370758/en

IEEE: Copy

H. EHTERAM, and B. SHAFAGHI, “PARENTAL LABORATORY FINDINGS OF PATIENTS WITH HOMOZYGOUS THALASSEMIA REFERRED TO IMMAM HOSSEIN HOSPITAL(1998) ,” FEYZ, vol. 4, no. 13, pp. 81–88, 2000, [Online]. Available: https://sid.ir/paper/370758/en

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