STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002)

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CHAHKANDI T.

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Journal: Journal of Sabzevar University of Medical Sciences Year:2003 | Volume:10 | Issue:2 (28) Page(s): 58-63

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Title

STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002)

Author(s)

CHAHKANDI T. | Issue Writer Certificate

Keywords

THALASSEMIAQ3

HEMOGLOBIN A2 AND FQ4

HEMATOLOGIC PARAMETERSQ2

Abstract

THALASSEMIAs are the most common disorders in Hemoglobin production characterized by a reduction in Hemoglobin synthesis. With different genetic characteristics in each society, the carriers may experimentally have different phenotype characteristics. This research was conducted to determine the conditions of experimental findings in the parents of infants suffering from major THALASSEMIA. 42 parents were selected to be studied in this descriptive study as for their CBC, MCV, MCH, the number of Hb, RBC, and F and A 2 Hemoglobin; 2 ml blood was taken from each and put in vials containing K3EDTA for CBC by means of ABX cell counter and Hemoglobin electrophoresis with cellulose acetat in alkaline PH and sent to laboratory. MCV lower than 80 ft, MCH lower than 27 pg and HBA 2 higher than 3.5% were respectively considered as major disorders in CBC and Hemoglobin electrophoresis. In all cases, MCV, MCH and HBA 2 were absolutely different from the normal range; the reference ranges for MCV and MCH are 65-73.7 and 17.7-24pg respectively. RBC was higher in 64.3% and lower in 33.3% than the normal range (0.8%-1.4%). The differences observed in this study may be attributed to the variety of genetic mutations especially to the rather high number of mutated genes in Iran; this implies further research in other geographical areas.

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APA: Copy

CHAHKANDI, T.. (2003). STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002). JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 10(2 (28)), 58-63. SID. https://sid.ir/paper/82520/en

Vancouver: Copy

CHAHKANDI T.. STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002). JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2003;10(2 (28)):58-63. Available from: https://sid.ir/paper/82520/en

IEEE: Copy

T. CHAHKANDI, “STUDY OF THE HMATOLOGIC PARAMETERS AND F AND A2 HEMOGLOBLIN IN PARENTS OF PATIENTS SUFFERRING FROM MAJOR THALASSEMIA IN BIRJAND IN 1381 (2002),” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 10, no. 2 (28), pp. 58–63, 2003, [Online]. Available: https://sid.ir/paper/82520/en

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