ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE

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NAZARI HOSSEIN; BIDOKHTY SHAYAN; MOHAMMADI ABOLFAZL; JAFARI MARYAM; TAHERIAN ABBAS ALI

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Journal: Koomesh Year:2017 | Volume:19 | Issue:1 (65) Page(s): 154-163

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Title

ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE

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Keywords

LAUNAEA ACANTHODESQ1

PERIPHERAL PAINQ1

VISCERAL PAINQ2

MICEQ2

Abstract

Introduction: Previous studies indicated that LAUNAEA ACANTHODES (LA) can be effective against epilepsy, nervous disorder, local and articular pain and convulsion disorders. The aim of this study was to assessment the antinoceceptive effects of LA on peripheral and VISCERAL PAIN in MICE by using hot plate (HP), tail flick (TF), formalin (FT) and writhing (WR) tests.Materials and Methods: In this study 160 young adult male albino MICE (25-30 g) were used (n=8 in each group). Aqueous extract of LA gum (50, 100, and 200 mg/Kg IP) and saline (SAL) were injected 30 min before the pain evaluation tests. Acute and chronic pain was assessed by HP, TF and FT models and VISCERAL PAIN was assessed by writhing test.Results: Results indicated that LA has analgesic effects (P<0.05) in comparison with the control and saline groups and higher dose of LA was more effective (P<0.001).Conclusion: The above findings showed that LA have modulatory effects on acute, chronic and VISCERAL PAIN.

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APA: Copy

NAZARI, HOSSEIN, BIDOKHTY, SHAYAN, MOHAMMADI, ABOLFAZL, JAFARI, MARYAM, & TAHERIAN, ABBAS ALI. (2017). ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE. KOOMESH, 19(1 (65)), 154-163. SID. https://sid.ir/paper/37118/en

Vancouver: Copy

NAZARI HOSSEIN, BIDOKHTY SHAYAN, MOHAMMADI ABOLFAZL, JAFARI MARYAM, TAHERIAN ABBAS ALI. ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE. KOOMESH[Internet]. 2017;19(1 (65)):154-163. Available from: https://sid.ir/paper/37118/en

IEEE: Copy

HOSSEIN NAZARI, SHAYAN BIDOKHTY, ABOLFAZL MOHAMMADI, MARYAM JAFARI, and ABBAS ALI TAHERIAN, “ANTINOCICEPTIVE EFFECTS OF AQEOUS EXTRACT LAUNAEA ACANTHODES GUM IN MICE,” KOOMESH, vol. 19, no. 1 (65), pp. 154–163, 2017, [Online]. Available: https://sid.ir/paper/37118/en

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