THE STUDY ON IMMUNIZATION OF BALB/C MICE AGAINST LEISHMANIA MAJOR BY SAUROLEISHMANIA

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KAZEMI B.; BAYAT M.; LABIBI F.

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Journal: Iranian Journal of Basic Medical Sciences Year:2002 | Volume:5 | Issue:3 (15) Page(s): 0-0

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Title

THE STUDY ON IMMUNIZATION OF BALB/C MICE AGAINST LEISHMANIA MAJOR BY SAUROLEISHMANIA

Author(s)

KAZEMI B. | BAYAT M. | LABIBI F. | Issue Writer Certificate

Keywords

SAUROLEISHMANIAQ4

LEISHMANIA MAJORQ2

IMMUNIZATIONQ2

BALB/C MICEQ3

Abstract

Zoonotic cutaneous leishmaniasis is a social health problem. There have been many researches such as leishmanization and use of non-pathogenic strain to control disease, but they have failed. We immunized 28 BALB/C MICE by subcutaneous injection of 4x 105 live lizard leishmania promastigotes (a species of nonpathogenic leishmania promastigote). After 20 days, each mouse received a booster dose. After 30 days each were challenged by LEISHMANIA MAJOR promastigote. Macrophage - entranced promastigote was tested microscopically by macrophage peritoneal. aspiration. Mouse sample blood was given and cultured in NNN medium. We examined mouse visceral organs for leishmania amastigotes and did not observe leishmania amastigote in the experimental group, but they were observed in the control group. Only one of experimental mice exhibited leishmanial lesion, and all of the control mice had developed cutaneous leishmaniasis.

Cites

ISOLATING A 68 KDA PROTEIN FRACTION OF LIZARD LEISHMANIA PROMASTIGOTE

References

لیشمانیای مارمولک در ایران

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APA: Copy

KAZEMI, B., BAYAT, M., & LABIBI, F.. (2002). THE STUDY ON IMMUNIZATION OF BALB/C MICE AGAINST LEISHMANIA MAJOR BY SAUROLEISHMANIA. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 5(3 (15)), 0-0. SID. https://sid.ir/paper/373197/en

Vancouver: Copy

KAZEMI B., BAYAT M., LABIBI F.. THE STUDY ON IMMUNIZATION OF BALB/C MICE AGAINST LEISHMANIA MAJOR BY SAUROLEISHMANIA. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2002;5(3 (15)):0-0. Available from: https://sid.ir/paper/373197/en

IEEE: Copy

B. KAZEMI, M. BAYAT, and F. LABIBI, “THE STUDY ON IMMUNIZATION OF BALB/C MICE AGAINST LEISHMANIA MAJOR BY SAUROLEISHMANIA,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 5, no. 3 (15), pp. 0–0, 2002, [Online]. Available: https://sid.ir/paper/373197/en

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