Effect of Six Weeks Endurance Training on Gene Expression of Apoptotic and Anti-Apoptotic in Left Ventricle Cardiac of Elderly Male Rats

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Ahmadnia a.; FASHI M.; ASAD M.R.

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Paper Information

Journal: SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE) Year:2019 | Volume:11 | Issue:42 Page(s): 31-46

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Information Journal Paper

Title

Effect of Six Weeks Endurance Training on Gene Expression of Apoptotic and Anti-Apoptotic in Left Ventricle Cardiac of Elderly Male Rats

Author(s)

Ahmadnia a. | FASHI M. | ASAD M.R. | Issue Writer Certificate

Keywords

Caspase-3Q1

Metallothionein-2Q1

Left Ventricular TissueQ1

Continuous Endurance ActivityQ1

ApoptosisQ1

Abstract

The aim of this study was to evaluation the effect of 6 weeks continuous endurance training (CET) on Caspase-3 and Metallothionein-2 in left ventricular Cardiac tissue of male rats. 14 elderly male rats divided to two group’ s control (n=7) and endurance training (n=7) (65%-70% maximum speed). Gene expression of Caspase-3 and Metallothionein-2 were assessment by Real time-PCR and the quantification of gene expression levels using the formula 2-Δ Δ ct were used by Independent t-test. The results showed that the 6 weeks of d CET leads to non-significant decrease in Gene expression of Caspase-3 (P=0. 078) and non-significant increase of Metallothionein-2 (P=0. 513). It seems, continuous endurance training does not to cause apoptotic damage in elderly people and can be used in this population.

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APA: Copy

Ahmadnia, a., FASHI, M., & ASAD, M.R.. (2019). Effect of Six Weeks Endurance Training on Gene Expression of Apoptotic and Anti-Apoptotic in Left Ventricle Cardiac of Elderly Male Rats. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), 11(42 ), 31-46. SID. https://sid.ir/paper/374631/en

Vancouver: Copy

Ahmadnia a., FASHI M., ASAD M.R.. Effect of Six Weeks Endurance Training on Gene Expression of Apoptotic and Anti-Apoptotic in Left Ventricle Cardiac of Elderly Male Rats. SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE)[Internet]. 2019;11(42 ):31-46. Available from: https://sid.ir/paper/374631/en

IEEE: Copy

a. Ahmadnia, M. FASHI, and M.R. ASAD, “Effect of Six Weeks Endurance Training on Gene Expression of Apoptotic and Anti-Apoptotic in Left Ventricle Cardiac of Elderly Male Rats,” SPORT PHYSIOLOGY (RESEARCH ON SPORT SCIENCE), vol. 11, no. 42 , pp. 31–46, 2019, [Online]. Available: https://sid.ir/paper/374631/en

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