EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE

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NOKHOSTIN ROUHI B.; RAHMANINIA FARHAD; BABAEI PARVIN; BOHLOULI SH.

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Journal: OLYMPIC Year:2009 | Volume:16 | Issue:4 (SERIAL 44) Page(s): 49-57

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Title

EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE

Author(s)

NOKHOSTIN ROUHI B. | RAHMANINIA FARHAD | BABAEI PARVIN | BOHLOULI SH. | Issue Writer Certificate

Keywords

ANTIOXIDANTQ3

CREATINE KINASEQ4

FREE RADICALSQ2

MALONDEALDEHYDEQ2

Abstract

Oxygen FREE RADICALS are highly reactive species that are produced in increased quantities during strenuous exercise and can damage critical biological targets such as membrane phospholipids. The purpose of this study was to examine the effect of acute ascorbic acid supplementation on exercise-induced free radical production in healthy subjects. Sixteen healthy male, unfamiliar with the exercise protocol, randomly received either ANTIOXIDANT (AO) (1000 mg vitamin C) or placebo (P) 2h before a 30-min treadmill run at 75% Vo2max (0% gradient). Vitamin C and MALONDEALDEHYDE (MDA) were measured by HPLC and Creatin Kinase (CK) was measured by Autoanalyzer. ANOVA repeated measures with Bonferroni correction was used to compare results over the times and independent t-test was used to determine between groups differences Plasma vitamin C concentration increased significantly 2h after supplementation, immediately and 2h after exercise in AO group (P<0.05). Serum CREATINE KINASE increased significantly immediately and 2h after exercise in both groups (P<0.05) and 24h after exercise only in P group. MALONDEALDEHYDE increased significantly 2h after exercise only in P group (P<0.05). The results indicate that acute ascorbic acid supplementation prevented exercise-induced oxidative stress and muscle damage in these subjects.

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APA: Copy

NOKHOSTIN ROUHI, B., RAHMANINIA, FARHAD, BABAEI, PARVIN, & BOHLOULI, SH.. (2009). EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE. OLYMPIC, 16(4 (SERIAL 44)), 49-57. SID. https://sid.ir/paper/37717/en

Vancouver: Copy

NOKHOSTIN ROUHI B., RAHMANINIA FARHAD, BABAEI PARVIN, BOHLOULI SH.. EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE. OLYMPIC[Internet]. 2009;16(4 (SERIAL 44)):49-57. Available from: https://sid.ir/paper/37717/en

IEEE: Copy

B. NOKHOSTIN ROUHI, FARHAD RAHMANINIA, PARVIN BABAEI, and SH. BOHLOULI, “EFFECT OF ACUTE SUPPLEMENTATION OF VITAMIN C ON EXERCISE-INDUCED LIPID PEROXIDATION AND MUSCLE DAMAGE,” OLYMPIC, vol. 16, no. 4 (SERIAL 44), pp. 49–57, 2009, [Online]. Available: https://sid.ir/paper/37717/en

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