The Effect of Resistance Training Program with Citrulline-Malate on Blood Pressure, Nitric Oxide, and Vascular Endothelial Growth Factor in Postmenopausal Women with Prehypertension

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BEHPOUR N.; MORADI F.; TADIBI V.

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Journal: JOURNAL OF ADVANCED BIOMEDICAL SCIENCES Year:2020 | Volume:10 | Issue:1 Page(s): 1913-1923

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Title

The Effect of Resistance Training Program with Citrulline-Malate on Blood Pressure, Nitric Oxide, and Vascular Endothelial Growth Factor in Postmenopausal Women with Prehypertension

Author(s)

BEHPOUR N. | MORADI F. | TADIBI V. | Issue Writer Certificate

Keywords

prehypertensionQ1

resistance trainingQ1

menopausal womenQ2

citrulline malateQ1

vascular functionQ1

Abstract

Background & Objective: Blood pressure generally increases after menopause. Training modalities with a supplement can influence blood pressure indices. The present study aims at investigating the effect of eight-week resistance training with citrulline-malate consumption on blood pressure, Nitric Oxide (NO), and Vascular Endothelial Growth Factor (VEGF) in postmenopausal women with prehypertension Materials & Methods: The sample population is postmenopausal women with pre-hypertensive age ranging from 50 to 55 years old divided randomly into six groups, including “ training + supplement” , “ training + placebo” , “ training” , “ no training + supplement” , “ supplement” and “ placebo” . resistance training was held 3 sessions per week in which the training intensity was 45% to 55% IRM. The supplement included citrulline-malate (8 g) an hour before each training session. Blood pressure, NO, and VEGE were measured using a barometer and kit before and after the training sessions. Two-way analysis of variance test and Tukey’ s follow-up test were applied to analyze data. Results: The findings demonstrated that training leads to a decrease in systolic and diastolic blood pressures while an increase in NO and VEGF. The results showed that an eight-week period of citrulline-malate supplementation has decreased systolic and diastolic blood pressure. Besides, it was revealed that eight weeks of citrulline-malate administration made NO and VEGF increase. Also, the results indicated that the "exercise + supplement" group has had the greatest effect on increasing NO and VEGF and reducing systolic and diastolic blood pressure. Moreover, the findings proved that resistance training with citrulline-malate made systolic and diastolic blood pressures in menopausal women with prehypertension reduce. These effects are accompanied by rising levels of NO and VEGF. Conclusion: The findings revealed that the resistance training, which was applied in the present study, coupled with citrulline-malate supplementation, will improve blood pressure in postmenopausal women with hypertension.

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APA: Copy

BEHPOUR, N., MORADI, F., & TADIBI, V.. (2020). The Effect of Resistance Training Program with Citrulline-Malate on Blood Pressure, Nitric Oxide, and Vascular Endothelial Growth Factor in Postmenopausal Women with Prehypertension. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, 10(1 ), 1913-1923. SID. https://sid.ir/paper/381671/en

Vancouver: Copy

BEHPOUR N., MORADI F., TADIBI V.. The Effect of Resistance Training Program with Citrulline-Malate on Blood Pressure, Nitric Oxide, and Vascular Endothelial Growth Factor in Postmenopausal Women with Prehypertension. JOURNAL OF ADVANCED BIOMEDICAL SCIENCES[Internet]. 2020;10(1 ):1913-1923. Available from: https://sid.ir/paper/381671/en

IEEE: Copy

N. BEHPOUR, F. MORADI, and V. TADIBI, “The Effect of Resistance Training Program with Citrulline-Malate on Blood Pressure, Nitric Oxide, and Vascular Endothelial Growth Factor in Postmenopausal Women with Prehypertension,” JOURNAL OF ADVANCED BIOMEDICAL SCIENCES, vol. 10, no. 1 , pp. 1913–1923, 2020, [Online]. Available: https://sid.ir/paper/381671/en

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