THE EFFECT OF HYPERGLYCEMIA ON THE SEIZUR THRESHOLD INDUCED BY PTZ IN MICE

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SAMINI M.; SHAIAN MEHR A.; SHAFAROUDI H.

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2004 | Volume:62 | Issue:8 Page(s): 685-689

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Title

THE EFFECT OF HYPERGLYCEMIA ON THE SEIZUR THRESHOLD INDUCED BY PTZ IN MICE

Author(s)

SAMINI M. | SHAIAN MEHR A. | SHAFAROUDI H. | Issue Writer Certificate

Keywords

HYPERGLYCEMIAQ4

SEIZURE THRESHOLDQ4

PTZQ4

GABA ACTIVITYQ4

Abstract

Background: we studied the effect of HYPERGLYCEMIA on the SEIZURE THRESHOLD to PTZ in mice. Materials and Methods: In control group PTZ injected via the tail vein 30 min after saline injection. In test group glucose 40% was used via gastric gavage and the HYPERGLYCEMIA was approved by determination of plasma glucose concentration. Results: In control group plasma glucose was 300.93 mg/dl showing a significant difference in comparison with test group 97.15 mg/dl (P<0.001). After induction of HYPERGLYCEMIA we determined the SEIZURE THRESHOLD induced by PTZ.Conclusion: In conclusion, our results showed that in hyperglycemic mice the SEIZURE THRESHOLD to PTZ is reduced, probably because of decreasing the GABA ACTIVITY in the CNS.

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APA: Copy

SAMINI, M., SHAIAN MEHR, A., & SHAFAROUDI, H.. (2004). THE EFFECT OF HYPERGLYCEMIA ON THE SEIZUR THRESHOLD INDUCED BY PTZ IN MICE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 62(8), 685-689. SID. https://sid.ir/paper/38278/en

Vancouver: Copy

SAMINI M., SHAIAN MEHR A., SHAFAROUDI H.. THE EFFECT OF HYPERGLYCEMIA ON THE SEIZUR THRESHOLD INDUCED BY PTZ IN MICE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2004;62(8):685-689. Available from: https://sid.ir/paper/38278/en

IEEE: Copy

M. SAMINI, A. SHAIAN MEHR, and H. SHAFAROUDI, “THE EFFECT OF HYPERGLYCEMIA ON THE SEIZUR THRESHOLD INDUCED BY PTZ IN MICE,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 62, no. 8, pp. 685–689, 2004, [Online]. Available: https://sid.ir/paper/38278/en

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