PREVALENCE OF METALLO-β-LACTAMASE AMONG IMIPENEM-RESISTANT ACINETOBACTER SPP. ISOLATED FROM SELECTED HOSPITALS IN KARAJ (2010)

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MOHEBI A.; AGHAEI S.; MOHAMMADZADEH MOHAMMAD; TAVAKOLI M.

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Journal: Journal of Inflammatory Diseases Year:2012 | Volume:16 | Issue:2 (63) Page(s): 53-57

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Title

PREVALENCE OF METALLO-β-LACTAMASE AMONG IMIPENEM-RESISTANT ACINETOBACTER SPP. ISOLATED FROM SELECTED HOSPITALS IN KARAJ (2010)

Author(s)

MOHEBI A. | AGHAEI S. | MOHAMMADZADEH MOHAMMAD | TAVAKOLI M. | Issue Writer Certificate

Keywords

ACINETOBACTERQ2

ANTIBIOTIC-RESISTANTQ2

IMIPENEMQ2

METALLO-β-LACTAMASEQ2

NOSOCOMIAL INFECTIONSQ3

Abstract

Background: IMIPENEM-resistant ACINETOBACTER spp. resulting from metallo-b-lactamase (MBLs) -producing strains have been reported to be among important causes of NOSOCOMIAL INFECTIONS and of serious therapeutic problem worldwide.Objective: To determine the prevalence of metallo-b-lactamase among IMIPENEM-resistant ACINETOBACTER isolates based on phenotypic methods.Methods: This was an descriptive study in which 140 clinical isolates of ACINETOBACTER spp. were initially tested for IMIPENEM susceptibility and later for metallo-b-lactamase production using combined disk diffusion, double disk synergy test, and Hodge test during 2010. Antibiotic susceptibility of positive metallo-b-lactamase isolates were further evaluated by disk diffusion technique using CLSI methodology.Findings: Of 140 isolates, 29 (20.7%) were IMIPENEM-resistant ACINETOBACTER. Positive phonetypic test for metallo-b-lactamase was 24 (17.1%).Conclusion: The result of this study is indicative of growing number of NOSOCOMIAL INFECTIONS associated with multidrug-resistant ACINETOBACTER spp. in this region leading to difficulties in antibiotic therapy.

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APA: Copy

MOHEBI, A., AGHAEI, S., MOHAMMADZADEH, MOHAMMAD, & TAVAKOLI, M.. (2012). PREVALENCE OF METALLO-β-LACTAMASE AMONG IMIPENEM-RESISTANT ACINETOBACTER SPP. ISOLATED FROM SELECTED HOSPITALS IN KARAJ (2010). JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 16(2 (63)), 53-57. SID. https://sid.ir/paper/400138/en

Vancouver: Copy

MOHEBI A., AGHAEI S., MOHAMMADZADEH MOHAMMAD, TAVAKOLI M.. PREVALENCE OF METALLO-β-LACTAMASE AMONG IMIPENEM-RESISTANT ACINETOBACTER SPP. ISOLATED FROM SELECTED HOSPITALS IN KARAJ (2010). JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2012;16(2 (63)):53-57. Available from: https://sid.ir/paper/400138/en

IEEE: Copy

A. MOHEBI, S. AGHAEI, MOHAMMAD MOHAMMADZADEH, and M. TAVAKOLI, “PREVALENCE OF METALLO-β-LACTAMASE AMONG IMIPENEM-RESISTANT ACINETOBACTER SPP. ISOLATED FROM SELECTED HOSPITALS IN KARAJ (2010),” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 16, no. 2 (63), pp. 53–57, 2012, [Online]. Available: https://sid.ir/paper/400138/en

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