THE KEY ROLE OF TYPE IV COLLAGEN IN DEVELOPING RETINAL BASEMENT MEMBRANE IN MOUSE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NIKRAVESH M.R.; JALALI MAHDI; MOEIN A.A.; KARIMFAR MOHAMMAD HASAN; RAFIGHDOUST H.; MOHAMMADI SHABNAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES Year:2010 | Volume:18 | Issue:72 Page(s): 56-62

Download Full-Text

Persian Verion

View:

1,485

Download:

Cites:

Information Journal Paper

Title

THE KEY ROLE OF TYPE IV COLLAGEN IN DEVELOPING RETINAL BASEMENT MEMBRANE IN MOUSE

Author(s)

Keywords

COLLAGENASESQ2

EVOLUTIONQ2

EXTRACELLULAR MATRIXQ3

MICEQ3

RETINAQ3

Abstract

Introduction: Basement membranes are specialized extracellular matrices serve as development, proliferation and substrates for migration. Collagen fibers specially type IV, are the most important part of this area. As RETINA is one of the target organs in diabetes mellitus and diabetic retinopathy and diabetic nephropathy are major cause of end stage - renal and RETINAl diseases and resulting in increased in morbidity and mortality of effected individuals, therefore early diagnosis leads to better treatment.Objective: Investigation the appearance and distribution of collagen IV during gestational days and early postnatal period.Materials and Methods: 24 intact female Balb/c MICE were kept under normal nutrition and environment condition. After mating, vaginal plug was assumed as zero day of pregnancy. From (13th-18th) days, gestation pregnant MICE were scarified and their embryos as well as pups from 1st to 5th days were collected. For histochemichal studies, the head of specimens were fixed; histological preparations was done and by using monocolonal antibody against for tracing of collagen type IV were carried out.Results: Our finding revealed that amount of collagen IV in internal limiting membrane (ILM) and extra cellular matrix (ECM) of the RETINA appearance on embryonic 16thday and increase continuously until end stage of embryonic life. In addition, strong labeling was observed until 3rd day of postnatal period but these reactions did not increase significantly after these periods.Conclusion: These findings indicate that RETINAl development is dependent on different proteins by special regards specially collagen IV.

Cites

MATERNAL NEXPOSURE ON COLLAGEN TYPE IV PULMONARY CHANGES IN MOUSE OFFSPRING'S

References

No record.

Cite

APA: Copy

NIKRAVESH, M.R., JALALI, MAHDI, MOEIN, A.A., KARIMFAR, MOHAMMAD HASAN, RAFIGHDOUST, H., & MOHAMMADI, SHABNAM. (2010). THE KEY ROLE OF TYPE IV COLLAGEN IN DEVELOPING RETINAL BASEMENT MEMBRANE IN MOUSE. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 18(72), 56-62. SID. https://sid.ir/paper/40162/en

Vancouver: Copy

NIKRAVESH M.R., JALALI MAHDI, MOEIN A.A., KARIMFAR MOHAMMAD HASAN, RAFIGHDOUST H., MOHAMMADI SHABNAM. THE KEY ROLE OF TYPE IV COLLAGEN IN DEVELOPING RETINAL BASEMENT MEMBRANE IN MOUSE. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;18(72):56-62. Available from: https://sid.ir/paper/40162/en

IEEE: Copy

M.R. NIKRAVESH, MAHDI JALALI, A.A. MOEIN, MOHAMMAD HASAN KARIMFAR, H. RAFIGHDOUST, and SHABNAM MOHAMMADI, “THE KEY ROLE OF TYPE IV COLLAGEN IN DEVELOPING RETINAL BASEMENT MEMBRANE IN MOUSE,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 72, pp. 56–62, 2010, [Online]. Available: https://sid.ir/paper/40162/en

Related Journal Papers