Effect of Chronic Nicotine Administration on the Pro-oxidant Antioxidant Balance of Mice Serum: Role of Rosmarinic Acid

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHARAFI AHVAZI NAIM; DANESHI ERFAN; NIKKHOO BAHRAM; ROSHANI DAEM; REZAEI MOHAMMAD JAFAR; ASGARI HAMID REZA; ABOUZARIPOUR MORTEZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES Year:2020 | Volume:25 | Issue:2 (106) Page(s): 54-60

Download Full-Text

Persian Verion

View:

265

Download:

Cites:

Information Journal Paper

Title

Effect of Chronic Nicotine Administration on the Pro-oxidant Antioxidant Balance of Mice Serum: Role of Rosmarinic Acid

Author(s)

Keywords

AntioxidantsQ1

RosmarinusQ1

NicotineQ3

SerumQ2

Abstract

Background and Aim: In this experimental study, Nicotine has been recognized to result in oxidative stress by inducing the generation of reactive oxygen species. The current research was designed to investigate the protective effect of rosmarinic acid, a radical scavenger and antioxidant, on Pro oxidant anti-oxidant balance of Serum in Nicotine treated mice. Materials and Methods: Thirty-six mature male NMRI mice were divided into 6groups: (two controls, two Nicotine-treated [0. 5 mg/kg], and two Nicotine plus rosmarinic acid [10 mg/kg]) were used in this study and treated for 15 and 30days respectively. The standard protocol was used to measure pro-oxidant-antioxidant balance, superoxide dismutase, and Serum Catalase. Results: As compared to control group (90± 3. 03315 HK), the 15-day results, in Nicotinetreated group (100± 5. 17687 HK) there was a significant increase in the Serum PAB ratio. Similarly, for samples of the day 30, there was a significant increase in the Serum PAB ratio of Nicotine-treated group (106± 3. 52136 HK) versus control group (87± 1. 32916 HK) (P≤ 0. 05). SOD of 15(1. 21± 1. 12) and 30 days (1. 89± 0. 26) treated groups, showed significant decreased versus control groups (2. 90± 0. 09), (2. 82± 0. 08) respectively (P≤ 0. 05). Catalase of 15(12. 13± 2. 30) and 30 days (11. 57± 1. 42) treated groups, showed significant decreased versus control groups (25. 12± 2. 21), (24. 1± 1. 29) respectively (P≤ 0. 05). Conclusion: These results indicate that rosmarinic acid improves the level of antioxidant enzymes and modifies pro-oxidant-antioxidant imbalance.

Cites

No record.

References

No record.

Cite

APA: Copy

SHARAFI AHVAZI, NAIM, DANESHI, ERFAN, NIKKHOO, BAHRAM, ROSHANI, DAEM, REZAEI, MOHAMMAD JAFAR, ASGARI, HAMID REZA, & ABOUZARIPOUR, MORTEZA. (2020). Effect of Chronic Nicotine Administration on the Pro-oxidant Antioxidant Balance of Mice Serum: Role of Rosmarinic Acid. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 25(2 (106) ), 54-60. SID. https://sid.ir/paper/404518/en

Vancouver: Copy

SHARAFI AHVAZI NAIM, DANESHI ERFAN, NIKKHOO BAHRAM, ROSHANI DAEM, REZAEI MOHAMMAD JAFAR, ASGARI HAMID REZA, ABOUZARIPOUR MORTEZA. Effect of Chronic Nicotine Administration on the Pro-oxidant Antioxidant Balance of Mice Serum: Role of Rosmarinic Acid. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;25(2 (106) ):54-60. Available from: https://sid.ir/paper/404518/en

IEEE: Copy

NAIM SHARAFI AHVAZI, ERFAN DANESHI, BAHRAM NIKKHOO, DAEM ROSHANI, MOHAMMAD JAFAR REZAEI, HAMID REZA ASGARI, and MORTEZA ABOUZARIPOUR, “Effect of Chronic Nicotine Administration on the Pro-oxidant Antioxidant Balance of Mice Serum: Role of Rosmarinic Acid,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 2 (106) , pp. 54–60, 2020, [Online]. Available: https://sid.ir/paper/404518/en

Related Journal Papers