DIAGNOSTIC APPROACH TO PRIMARY IMMUNODEFICIENCY DISORDERS

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AGHAMOHAMMADI A.

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Journal: Iranian Journal of Pediatrics Year:2014 | Volume:24 | Issue:2 (SUPPLEMENT) Page(s): 33-33

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Information Journal Paper

Title

DIAGNOSTIC APPROACH TO PRIMARY IMMUNODEFICIENCY DISORDERS

Author(s)

AGHAMOHAMMADI A. | Issue Writer Certificate

Keywords

PRIMARY IMMUNODEFICIENCYQ4

DIAGNOSISQ4

Abstract

PRIMARY IMMUNODEFICIENCY disorders (PIDs) are a heterogeneous group of inherited disorders that affect different components of the immune system. During last years, advances in molecular genetics and immunology have resulted in the identification of a growing number of genes causing primary immunodeficiencies (PIDs) in human subjects. Since 1952, more than 220 different PID disorders which have been described. Despite progress in discovery of PIDs and understanding of pathogenesis of these disorders over the last 20 years, many patients remain undiagnosed. Recognition of PIDs may be difficult as infections are common in young children in particular. Identifying different clinical manifestations of PID is the first most important step of DIAGNOSIS of PID. Clues to the DIAGNOSIS of PID may be found in history, physical examination. Different diagnostic tools have been developed for DIAGNOSIS of primary immunodeficiencies. The investigations are largely guided by the clinical presentation of the patient, the suspected immune defect and the results of initial laboratory evaluation. This review will focus on essential and necessary laboratory approach for DIAGNOSIS of suspected cases of PID.

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APA: Copy

AGHAMOHAMMADI, A.. (2014). DIAGNOSTIC APPROACH TO PRIMARY IMMUNODEFICIENCY DISORDERS. IRANIAN JOURNAL OF PEDIATRICS, 24(2 (SUPPLEMENT)), 33-33. SID. https://sid.ir/paper/408123/en

Vancouver: Copy

AGHAMOHAMMADI A.. DIAGNOSTIC APPROACH TO PRIMARY IMMUNODEFICIENCY DISORDERS. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2014;24(2 (SUPPLEMENT)):33-33. Available from: https://sid.ir/paper/408123/en

IEEE: Copy

A. AGHAMOHAMMADI, “DIAGNOSTIC APPROACH TO PRIMARY IMMUNODEFICIENCY DISORDERS,” IRANIAN JOURNAL OF PEDIATRICS, vol. 24, no. 2 (SUPPLEMENT), pp. 33–33, 2014, [Online]. Available: https://sid.ir/paper/408123/en

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