SEASONAL VARIATION IN SERUM 25-HYDROXY VITAMIN D LEVEL IN TEHRAN URBAN RESIDENTS

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RAEISZADEH F.; MIRSAIED GHAZI A.A.; PEZESHK P.; AZIZI F.

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Journal: Research in Medicine Year:2002 | Volume:26 | Issue:2 Page(s): 101-106

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Title

SEASONAL VARIATION IN SERUM 25-HYDROXY VITAMIN D LEVEL IN TEHRAN URBAN RESIDENTS

Author(s)

RAEISZADEH F. | MIRSAIED GHAZI A.A. | PEZESHK P. | AZIZI F. | Issue Writer Certificate

Keywords

SUNLIGHTQ4

VITAMIN DQ2

SEASONAL VARIATIONQ4

Abstract

Background: VITAMIN D is an essential substance for bone health. VITAMIN D serum concentration has been shown to have a SEASONAL VARIATION in different countries, but this has not yet been studied in Iran. Materials and methods: In this study performed on participants of Tehran Lipid and Glucose Study (TLGS), we measured serum level of 25-hydroxy VITAMIN D (25-0H-D) in 1172 subjects (682 women and 490 men) aged 3-69 years, who were studied in different months of the year. No sampling was achieved in month 10 of Iranian calendar (January) due to coincidence with Ramadan fasting. 25-0H-D was measured by competitive protein binding assay using RIA kits, and serum levels below 20ng/ml were considered as VITAMIN D deficiency. Results: VITAMIN D serum level in our study population had a monthly variation pattern and the magnitude of variation was greater in males as compared to females. The lowest serum 25-0H-D levels were observed in December and February in both sexes (12±13 and 14±14 ng/ml in females and 28±16 and 24±18ng/ml in males, respectively), whereas the highest levels were seen in November (29±29ng/ml in females and 55±27ng/ml in males). In all months mean serum level of 25-0H-D in females was equal or less than that in males. The magnitude of monthly variations in females was lower than in males and the least difference between 25-0H-D level of the two sexes observed in summer. Mean 25-0H-D level in males in summer and Winter (31± 17 and 28±22ng/ml, respectively) is significantly lower than in spring and autumn (38±27 and 43± 29ng/ml; p<0.05 and p<0.01, respectively), but females have shown no significant difference between 25-0H-D levels during the first three seasons and only levels during winter were significantly lower than those of autumn (17±16 ng/ml vs. 23±23 ng/ml, p<0.05).Conclusion: The lower magnitude of SEASONAL VARIATION and the significantly lower levels of 25-0H-D in females in our study can be attributed to their life style and their conventional clothing worn without variation all throughout the year. Our findings signify the importance of further research and adoption of preventive public health strategies for metabolic bone diseases, especially during the winter.

Cites

ASSESSMENT OF VITAMIN D SUPPLEMENTATION EFFECT ON INSULIN RESISTANCE AMONG TYPE 2 DIABETIC PATIENTS

References

VITAMIN D DEFICIENCY IN TEHRAN URBAN POPULATION

Cite

APA: Copy

RAEISZADEH, F., MIRSAIED GHAZI, A.A., PEZESHK, P., & AZIZI, F.. (2002). SEASONAL VARIATION IN SERUM 25-HYDROXY VITAMIN D LEVEL IN TEHRAN URBAN RESIDENTS. PAJOUHESH DAR PEZESHKI, 26(2), 101-106. SID. https://sid.ir/paper/41836/en

Vancouver: Copy

RAEISZADEH F., MIRSAIED GHAZI A.A., PEZESHK P., AZIZI F.. SEASONAL VARIATION IN SERUM 25-HYDROXY VITAMIN D LEVEL IN TEHRAN URBAN RESIDENTS. PAJOUHESH DAR PEZESHKI[Internet]. 2002;26(2):101-106. Available from: https://sid.ir/paper/41836/en

IEEE: Copy

F. RAEISZADEH, A.A. MIRSAIED GHAZI, P. PEZESHK, and F. AZIZI, “SEASONAL VARIATION IN SERUM 25-HYDROXY VITAMIN D LEVEL IN TEHRAN URBAN RESIDENTS,” PAJOUHESH DAR PEZESHKI, vol. 26, no. 2, pp. 101–106, 2002, [Online]. Available: https://sid.ir/paper/41836/en

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