ASSOCIATION OF HER2 WITH PROGNOSTIC FACTORS OF BREAST CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOFID B.; JALALI N M.R.; KIANI L.; ZAYERI F.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Research in Medicine Year:2004 | Volume:28 | Issue:1 Page(s): 29-32

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,353

Download:

Cites:

Information Journal Paper

Title

ASSOCIATION OF HER2 WITH PROGNOSTIC FACTORS OF BREAST CANCER

Author(s)

MOFID B. | JALALI N M.R. | KIANI L. | ZAYERI F. | Issue Writer Certificate

Keywords

HER2Q2

ESTROGEN RECEPTORQ2

PROGESTERONE RECEPTORQ3

AXILLARY LYMPH NODEQ3

BREAST CANCERQ4

Abstract

Background: BREAST CANCER is the most common female malignancy world wide and in Iran as well and is the second cause of death due to malignancy after lung cancer. Varieties of factors such as estrogen and PROGESTERONE RECEPTORs, and AXILLARY LYMPH NODE involvement may influence the prognosis and therapeutic approach. However, mutation in HER2 gene may also affect the prognosis. In this study, we evaluate the relation between HER2, estrogen and PROGESTERONE RECEPTORs and AXILLARY LYMPH NODE involvement, in primary breast carcinoma.Materials and methods: For this cross-sectional study, 102 patients with primary BREAST CANCER were enrolled. Having prepared the sections, they were stained by H & E. Then, the size and type of tumor, severity, and number of involved lymph nodes were determined. On the other hand, we have identified the estrogen, progesterone and HER2according to the immunohistochemiostry staining.Results: Of 102 subjects, 65 (73.7%) were HER2 positive. We have found a significant association between the HER2 and number of involved lymph nodes (p<0.007), however, our results failed to show any significant association between estrogen and PROGESTERONE RECEPTORs and severity of diseases. Conclusion: The high frequency of HER2 gene mutation draws our attention towards the importance of this marker among Iranians, however, to confirm the role of HER2in BREAST CANCER prognosis, we must conduct further studies.

Cites

References

No record.

Cite

APA: Copy

MOFID, B., JALALI N, M.R., KIANI, L., & ZAYERI, F.. (2004). ASSOCIATION OF HER2 WITH PROGNOSTIC FACTORS OF BREAST CANCER. PAJOUHESH DAR PEZESHKI, 28(1), 29-32. SID. https://sid.ir/paper/42042/en

Vancouver: Copy

MOFID B., JALALI N M.R., KIANI L., ZAYERI F.. ASSOCIATION OF HER2 WITH PROGNOSTIC FACTORS OF BREAST CANCER. PAJOUHESH DAR PEZESHKI[Internet]. 2004;28(1):29-32. Available from: https://sid.ir/paper/42042/en

IEEE: Copy

B. MOFID, M.R. JALALI N, L. KIANI, and F. ZAYERI, “ASSOCIATION OF HER2 WITH PROGNOSTIC FACTORS OF BREAST CANCER,” PAJOUHESH DAR PEZESHKI, vol. 28, no. 1, pp. 29–32, 2004, [Online]. Available: https://sid.ir/paper/42042/en

Related Journal Papers