REVIEW OF APPLICATIONS OF TETRACYCLINES IN OPHTHALMOLOGY

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SHAHRIARI M.; BEHNAZ N.; JAVADI M.A.

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Journal: BINA Year:2015 | Volume:21 | Issue:1 (82) Page(s): 61-69

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Information Journal Paper

Title

REVIEW OF APPLICATIONS OF TETRACYCLINES IN OPHTHALMOLOGY

Author(s)

SHAHRIARI M. | BEHNAZ N. | JAVADI M.A. | Issue Writer Certificate

Keywords

ANTI-INFLAMMATIONQ3

DOXYCYCLINEQ3

MINOCYCLINEQ3

OPHTHALMOLOGYQ3

TETRACYCLINEQ3

Abstract

Tetracyclines are broad spectrum antibiotics which are inexpensive and widely available and have an appropriate safety profile. In addition to antibiotical effects, TETRACYCLINEs can inhibit matrix metaloproteinase and collagenase, and subsequently reduce inflammation, angiogenesis, and neovascularization. They have partial neuro-protective, anti-apoptotic and antioxidant properties. Given these properties, TETRACYCLINEs are commonly used for the management of some ocular diseases such as pdry eye, blepharitis, meibomian gland dysfunction, rosacea, chemical burn, vesicant injuries, graft rejection reactions, and pterygium. Subantibacterial doses (20-100 mg/day) are used for the aforementioned purposes. Recently some studies investigated the neuro-protective, anti-oxidant and anti-apoptotic properties of TETRACYCLINEs which can be exploited for some neuroretinal diseases including retinopathies and ischemia-reperfusion injuries. However, more studies are needed for these new applications of TETRACYCLINEs.

Cites

NEW DEVELOPMENT IN THE MANAGEMENT OF DRY EYE SYNDROME

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APA: Copy

SHAHRIARI, M., BEHNAZ, N., & JAVADI, M.A.. (2015). REVIEW OF APPLICATIONS OF TETRACYCLINES IN OPHTHALMOLOGY. BINA, 21(1 (82)), 61-69. SID. https://sid.ir/paper/42538/en

Vancouver: Copy

SHAHRIARI M., BEHNAZ N., JAVADI M.A.. REVIEW OF APPLICATIONS OF TETRACYCLINES IN OPHTHALMOLOGY. BINA[Internet]. 2015;21(1 (82)):61-69. Available from: https://sid.ir/paper/42538/en

IEEE: Copy

M. SHAHRIARI, N. BEHNAZ, and M.A. JAVADI, “REVIEW OF APPLICATIONS OF TETRACYCLINES IN OPHTHALMOLOGY,” BINA, vol. 21, no. 1 (82), pp. 61–69, 2015, [Online]. Available: https://sid.ir/paper/42538/en

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