PREVENTIVE EFFECT OF PROPOFOL AGAINST INCREASED INTRA-OCULAR PRESSURE CAUSED BY SUCCINYLCHOLINE INJECTION AND ENDO-TRACHEAL INTUBATION

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SABER MOGHADAM RANJBAR MOHSEN; ALAVINIA S.M.

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Journal: Journal of Mazandaran University of Medical Sciences Year:2010 | Volume:20 | Issue:76 Page(s): 89-94

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Title

PREVENTIVE EFFECT OF PROPOFOL AGAINST INCREASED INTRA-OCULAR PRESSURE CAUSED BY SUCCINYLCHOLINE INJECTION AND ENDO-TRACHEAL INTUBATION

Author(s)

SABER MOGHADAM RANJBAR MOHSEN | ALAVINIA S.M. | Issue Writer Certificate

Keywords

SUCCINYLCHOLINEQ3

INTRA-OCULAR PRESSUREQ3

RAPID SEQUENCE INDUCTIONQ3

PROPOFOLQ3

Abstract

Background and purpose: Penetrating eye injury is one of the most frequent trauma admitted in ophtalmological emergency rooms. The major concern when treating such a trauma is increased intraocular pressure and vitreous loss as a side effect of SUCCINYLCHOLINE and endotracheal intubation with no appropriate substitute drug available yet.This study is aimed to determine whether the use of PROPOFOL can prevent the increase INTRA-OCULAR PRESSURE caused by SUCCINYLCHOLINE injection and endotracheal intubation.Materials and methods: 46 cases were selected and classified on the basis of American Society of Anesthesiologists’ Physical Status I, II (ASAPS I, II). Before induction of an aesthesia, INTRA-OCULAR PRESSURE was measured for each individual case using Schiotz tonometer. Then, anaesthesia was carried out using PROPOFOL (mean: 3 mg/kg) and SUCCINYLCHOLINE (mean: 1.2 mg/kg) while endo-tracheal tube being placed in the trachea. INTRA-OCULAR PRESSURE was measured using the same method immediately and 2 minutes after intubation.Repeated measurements test and correlation co-efficient was used to compare the mean difference and correlation between measurements. SPSS version 16 and SAS-9.1 were used to conduct all statistical analysis.Results: 33 patients, of them 13 female cases (39.4%) and 20 male (60.6%) cases have shown a mean intar-ocular pressure of 12 mmHg prior to induction. After intubation, their immediate and two minutes intar-ocular pressure were 10.69 and 9.93 mmHg respectively.Conclusion: Our study shows not only the INTRA-OCULAR PRESSURE is not raised but also it is decreased by rapid induction of PROPOFOL followed by injection of SUCCINYLCHOLINE and endotracheal intubation.

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APA: Copy

SABER MOGHADAM RANJBAR, MOHSEN, & ALAVINIA, S.M.. (2010). PREVENTIVE EFFECT OF PROPOFOL AGAINST INCREASED INTRA-OCULAR PRESSURE CAUSED BY SUCCINYLCHOLINE INJECTION AND ENDO-TRACHEAL INTUBATION. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 20(76), 89-94. SID. https://sid.ir/paper/44976/en

Vancouver: Copy

SABER MOGHADAM RANJBAR MOHSEN, ALAVINIA S.M.. PREVENTIVE EFFECT OF PROPOFOL AGAINST INCREASED INTRA-OCULAR PRESSURE CAUSED BY SUCCINYLCHOLINE INJECTION AND ENDO-TRACHEAL INTUBATION. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;20(76):89-94. Available from: https://sid.ir/paper/44976/en

IEEE: Copy

MOHSEN SABER MOGHADAM RANJBAR, and S.M. ALAVINIA, “PREVENTIVE EFFECT OF PROPOFOL AGAINST INCREASED INTRA-OCULAR PRESSURE CAUSED BY SUCCINYLCHOLINE INJECTION AND ENDO-TRACHEAL INTUBATION,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 20, no. 76, pp. 89–94, 2010, [Online]. Available: https://sid.ir/paper/44976/en

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