EFFECT OF SMALL-DOSE OF EPHEDRINE ADMINISTERED PRIOR TO INDUCTION OF ANESTHESIA ON THE ONSET TIME OF SUCCINYLCHOLINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ATASHKHOUEI S.; NEGARGAR S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Armaghane Danesh Year:2007 | Volume:12 | Issue:3 (47) Page(s): 1-9

Download Full-Text

Persian Verion

View:

934

Download:

Cites:

Information Journal Paper

Title

EFFECT OF SMALL-DOSE OF EPHEDRINE ADMINISTERED PRIOR TO INDUCTION OF ANESTHESIA ON THE ONSET TIME OF SUCCINYLCHOLINE

Author(s)

ATASHKHOUEI S. | NEGARGAR S. | Issue Writer Certificate

Keywords

EPHEDRINEQ3

RAPID-SEQUENCE INDUCTION OF ANESTHESIAQ3

ONSET TIME OF SUCCINYLCHOLINEQ3

Abstract

Introduction & Objective: Onset of action of relaxants is influenced by cardiac output and muscle blood flow. EPHEDRINE increases blood flow to muscles and may shorten the onset of action of succinylcholine. The aim of this study was to evaluate the effect of small-dose of EPHEDRINE administered prior to rapidsequence induction of anesthesia on the ONSET TIME OF SUCCINYLCHOLINE for endotracheal intubation. Materials & Methods: In this randomized clinical trial, 60 patients scheduled for elective gynecologic surgeries in Alzahra hospital in Tabriz 1385, were selected. In these patients EPHEDRINE, 70 mg/kg (study group, n=30), or saline (placebo group, n=30) was administered 3 minutes before induction of anesthesia with thiopentone/fentanyl. Succinylcholine, 0.6 mg/kg, was administrated to facilitate the tracheal intubation. Onset of succinylcholine, intubating conditions and hemodynamic variables were recorded in the subjects. Results: Fasciculation was absent in 60% (36) of the patients. No significant differences were found between the onsets of fasciculation between two groups. Moreover, the difference in duration of fasciculation in two groups was not significant. ONSET TIME OF SUCCINYLCHOLINE was significantly shorter in study group (19.53±3.91 second), compared with placebo group (25.87±7.11 second) (p<0.0001). Patients in study group were intubated in 47.07±4.51 seconds compared with 58.73±9.04 seconds in placebo group (p<0.0001). Intubation conditions were similar in both groups. Heart rate was slightly increased in study patients in the first and 3rd minutes after EPHEDRINE administration, but there was no significant difference in systolic blood pressure values compared with the baseline value between two groups.Conclusion: The ONSET TIME OF SUCCINYLCHOLINE is shortened with small-dose of EPHEDRINE pretreatment without significant adverse heamodynamic effects.

Cites

No record.

References

EFFECT OF SMALL DOSES OF SUCCINYLCHOLINE ON TRACHEAL INTUBATION CONDITIONS

Cite

APA: Copy

ATASHKHOUEI, S., & NEGARGAR, S.. (2007). EFFECT OF SMALL-DOSE OF EPHEDRINE ADMINISTERED PRIOR TO INDUCTION OF ANESTHESIA ON THE ONSET TIME OF SUCCINYLCHOLINE. ARMAGHAN DANESH, 12(3 (47)), 1-9. SID. https://sid.ir/paper/77683/en

Vancouver: Copy

ATASHKHOUEI S., NEGARGAR S.. EFFECT OF SMALL-DOSE OF EPHEDRINE ADMINISTERED PRIOR TO INDUCTION OF ANESTHESIA ON THE ONSET TIME OF SUCCINYLCHOLINE. ARMAGHAN DANESH[Internet]. 2007;12(3 (47)):1-9. Available from: https://sid.ir/paper/77683/en

IEEE: Copy

S. ATASHKHOUEI, and S. NEGARGAR, “EFFECT OF SMALL-DOSE OF EPHEDRINE ADMINISTERED PRIOR TO INDUCTION OF ANESTHESIA ON THE ONSET TIME OF SUCCINYLCHOLINE,” ARMAGHAN DANESH, vol. 12, no. 3 (47), pp. 1–9, 2007, [Online]. Available: https://sid.ir/paper/77683/en

Related Journal Papers