QUANTIFICATION OF MAST CELLS IN PERIODONTALLY DISEASED AND HEALTHY TISSUES

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SEYYEDMAJIDI MARYAM; DABBAGH SATTARI FARHAD; FAELIGHADIKOLAEI ROGHAIEH; GHOLINIA HEMMAT

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Journal: Journal of Mazandaran University of Medical Sciences Year:2017 | Volume:26 | Issue:144 Page(s): 203-210

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Title

QUANTIFICATION OF MAST CELLS IN PERIODONTALLY DISEASED AND HEALTHY TISSUES

Author(s)

SEYYEDMAJIDI MARYAM | DABBAGH SATTARI FARHAD | FAELIGHADIKOLAEI ROGHAIEH | GHOLINIA HEMMAT | Issue Writer Certificate

Keywords

MAST CELLSQ1

PERIODONTAL DISEASEQ2

PERIODONTITISQ2

GINGIVITISQ2

Abstract

Background and purpose: PERIODONTITIS and GINGIVITIS are inflammatory diseases in supporting tissues of tooth. MAST CELLS are inflammatory cells that can participate in destruction of connective tissue in PERIODONTAL DISEASEs. In this study we evaluated MAST CELLS count in gingival tissues in individuals with PERIODONTAL DISEASEs and compared that with those in healthy people.Materials and methods: This case-control study was done in 60 samples obtained from patients with advanced PERIODONTITIS (n=15), moderate PERIODONTITIS (n=15), GINGIVITIS (n=15), and healthy tissue samples (n=15, control group). Biopsy specimens obtained during flap and crown lengthening surgery were stained with toluidine blue and hematoxylin eosin.Results: MAST CELLS count were significantly different between four groups (P<0.001). In fact a significant difference was found in healthy status compared to that in moderate PERIODONTITIS, advanced PERIODONTITIS and GINGIVITIS (P<0.001) but it did not show any significant difference in advanced and moderate PERIODONTITIS compared with that in GINGIVITIS (P>0.05). Also, MAST CELLS count did not reveal any significant difference between advanced PERIODONTITIS and moderate PERIODONTITIS (P>0.05). Moreover, we found no significant relationship between MAST CELLS count and degree of microscopic inflammation (P=0.09).Conclusion: MAST CELLS are believed to play a role in pathogenesis of PERIODONTAL DISEASEs, but further studies are suggested to clarify this role.

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APA: Copy

SEYYEDMAJIDI, MARYAM, DABBAGH SATTARI, FARHAD, FAELIGHADIKOLAEI, ROGHAIEH, & GHOLINIA, HEMMAT. (2017). QUANTIFICATION OF MAST CELLS IN PERIODONTALLY DISEASED AND HEALTHY TISSUES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 26(144), 203-210. SID. https://sid.ir/paper/45389/en

Vancouver: Copy

SEYYEDMAJIDI MARYAM, DABBAGH SATTARI FARHAD, FAELIGHADIKOLAEI ROGHAIEH, GHOLINIA HEMMAT. QUANTIFICATION OF MAST CELLS IN PERIODONTALLY DISEASED AND HEALTHY TISSUES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;26(144):203-210. Available from: https://sid.ir/paper/45389/en

IEEE: Copy

MARYAM SEYYEDMAJIDI, FARHAD DABBAGH SATTARI, ROGHAIEH FAELIGHADIKOLAEI, and HEMMAT GHOLINIA, “QUANTIFICATION OF MAST CELLS IN PERIODONTALLY DISEASED AND HEALTHY TISSUES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 144, pp. 203–210, 2017, [Online]. Available: https://sid.ir/paper/45389/en

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