COMPARE THE EFFICACY OF LITHIUM CARBONATE & SODIUM VALPROATE IN TREATMENT OF BIPOLAR CHILDREN AND ADOLESCENTS IN ACUTE PHASE (MIXED & MANIA) TREATMENT AT ROOZBEH HOSPITAL

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SHAFAAT A.; SHAHRIVAR Z.; ALAGHBANDRAD J.; KAVIANI HOSSEIN

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Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2008 | Volume:18 | Issue:66 Page(s): 26-34

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Title

COMPARE THE EFFICACY OF LITHIUM CARBONATE & SODIUM VALPROATE IN TREATMENT OF BIPOLAR CHILDREN AND ADOLESCENTS IN ACUTE PHASE (MIXED & MANIA) TREATMENT AT ROOZBEH HOSPITAL

Author(s)

SHAFAAT A. | SHAHRIVAR Z. | ALAGHBANDRAD J. | KAVIANI HOSSEIN | Issue Writer Certificate

Keywords

LITHIUM CARBONATEQ3

SODIUM VALPROATEQ2

YOUNG MANIA RATING SCALEQ3

TREATMENTQ4

CHILD &ADOLESCENT BIPOLAR MOOD DISORDERQ4

Abstract

Background and Purpose: To compare the efficacy of LITHIUM CARBONATE &sodium valproate in TREATMENT of bipolar children and adolescents in acute phase (mixed &mania) in 6 week TREATMENT at Roozbeh hospital.Materials and methods: A double-blind & randomized controlled clinical trial in 30 patient (8-18 years) for a 6 week trial patients were diagnosed based on DSM_IV criteria through clinical interview & K_SADS.MRS & CGAS were used to measure the severity of symptoms and the level of functional impairment patients categorized into 2 groups randomly.Results: In both groups means of MRS decreased (at the end of 3rd&6th weeks) and there was no significant difference between two groups. Means of CGAS had significant difference between two groups at 3rd week (p<0.05).patient who received SODIUM VALPROATE had more improvement in function, but it was not at end of 6th week.Conclusion: The study demonstrated the same amount of decrease in sign and severity of symptoms and the same improvement in global functioning in tow groups. It seems that the efficacy of LITHIUM CARBONATE & SODIUM VALPROATE in acute phase of bipolar disorder is the same greater improvement of functioning at the end of the 3rd week in valproate group comparing to the lithium group suggests that SODIUM VALPROATE may act faster than LITHIUM CARBONATE. This replicate in future research.

Cites

THE EFFECT OF SIX WEEKS OF SELECTED AEROBIC TRAINING ON SOME RELATED MARKERS OF BIPOLAR Ι DISORDERS

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APA: Copy

SHAFAAT, A., SHAHRIVAR, Z., ALAGHBANDRAD, J., & KAVIANI, HOSSEIN. (2008). COMPARE THE EFFICACY OF LITHIUM CARBONATE & SODIUM VALPROATE IN TREATMENT OF BIPOLAR CHILDREN AND ADOLESCENTS IN ACUTE PHASE (MIXED & MANIA) TREATMENT AT ROOZBEH HOSPITAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 18(66), 26-34. SID. https://sid.ir/paper/45658/en

Vancouver: Copy

SHAFAAT A., SHAHRIVAR Z., ALAGHBANDRAD J., KAVIANI HOSSEIN. COMPARE THE EFFICACY OF LITHIUM CARBONATE & SODIUM VALPROATE IN TREATMENT OF BIPOLAR CHILDREN AND ADOLESCENTS IN ACUTE PHASE (MIXED & MANIA) TREATMENT AT ROOZBEH HOSPITAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;18(66):26-34. Available from: https://sid.ir/paper/45658/en

IEEE: Copy

A. SHAFAAT, Z. SHAHRIVAR, J. ALAGHBANDRAD, and HOSSEIN KAVIANI, “COMPARE THE EFFICACY OF LITHIUM CARBONATE & SODIUM VALPROATE IN TREATMENT OF BIPOLAR CHILDREN AND ADOLESCENTS IN ACUTE PHASE (MIXED & MANIA) TREATMENT AT ROOZBEH HOSPITAL,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 66, pp. 26–34, 2008, [Online]. Available: https://sid.ir/paper/45658/en

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