THE EFFECT OF BUPIVACAINE-CLONIDINE COMBINATION IN QUALITY AND DURATION OF CAUDAL BLOCK IN CHILDREN BETWEEN 2-7 YEARS OLD

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SEYED HEJAZI M.; KALAMI L.; NEGARGAR S.; ASLANABADI S.; NAGHIZADEH S.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2008 | Volume:30 | Issue:2 Page(s): 63-67

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Title

THE EFFECT OF BUPIVACAINE-CLONIDINE COMBINATION IN QUALITY AND DURATION OF CAUDAL BLOCK IN CHILDREN BETWEEN 2-7 YEARS OLD

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Keywords

PEDIATRICQ3

CAUDAL BLOCKQ3

CLONIDINEQ3

BUPIVACAINEQ3

Abstract

Background and Objectives: Caudal epidural block is one of the most common regional anesthetic techniques used in neonate and children. Stable hemodynamics and prevention of nero transmitter release after CAUDAL BLOCK in postoperative period leads to facilitation of surgical wound repair, reducing parents anxiety, surgeons satisfaction, decreasing hospitalization time and finance Aim of this study was assessment of supplementation of local anesthetic drugs with clonidin in epidural caudal anesthesia to increase duration and quality of analgesia.Methods: One hundred children aged 2-7 years, scheduled for elective lower abdominal surgery, were evaluated in this prospective randomized double blind and placebo controlled clinical trial in two equal groups to receive 0.25% bupivacain 1ml/kg combined with either CLONIDINE 2µg/kg (group 1) or 1ml normal saline (group 2). Method of anesthesia was similar in both groups .analgesic consumption, systolic and diastolic blood pressure and heart rate were recorded.Results: Three patients (6%) in group 1 (first 1-2 hours) and 21 patients (42%) in group 2(up to 8 hours) required supplementary analgesia after operation (P<0.001). According to P values there were significant differences between two groups in the mean of systolic blood pressure (P<0.01), diastolic blood pressure (P<0.013) and heart rate (P<0.001).Conclusion: It seems that when added to BUPIVACAINE, CLONIDINE improves the efficacy and lengths of caudal analgesia in children.

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APA: Copy

SEYED HEJAZI, M., KALAMI, L., NEGARGAR, S., ASLANABADI, S., & NAGHIZADEH, S.. (2008). THE EFFECT OF BUPIVACAINE-CLONIDINE COMBINATION IN QUALITY AND DURATION OF CAUDAL BLOCK IN CHILDREN BETWEEN 2-7 YEARS OLD. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 30(2), 63-67. SID. https://sid.ir/paper/47067/en

Vancouver: Copy

SEYED HEJAZI M., KALAMI L., NEGARGAR S., ASLANABADI S., NAGHIZADEH S.. THE EFFECT OF BUPIVACAINE-CLONIDINE COMBINATION IN QUALITY AND DURATION OF CAUDAL BLOCK IN CHILDREN BETWEEN 2-7 YEARS OLD. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;30(2):63-67. Available from: https://sid.ir/paper/47067/en

IEEE: Copy

M. SEYED HEJAZI, L. KALAMI, S. NEGARGAR, S. ASLANABADI, and S. NAGHIZADEH, “THE EFFECT OF BUPIVACAINE-CLONIDINE COMBINATION IN QUALITY AND DURATION OF CAUDAL BLOCK IN CHILDREN BETWEEN 2-7 YEARS OLD,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 30, no. 2, pp. 63–67, 2008, [Online]. Available: https://sid.ir/paper/47067/en

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