RELATIONSHIP BETWEEN SMOKING STATUS, VITAMIN B12 AND FOLIC ACID, WITH HOMOCYSTEINE IN PATIENTS WITH ISCHEMIC STROKE

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MONSHI KARIMI ALIREZA; MOHTADI NIA JAVAD; FARHOODI MAHDI; AREF HOSSEINI SAYED RAFI

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Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2011 | Volume:33 | Issue:2 Page(s): 81-86

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Title

RELATIONSHIP BETWEEN SMOKING STATUS, VITAMIN B12 AND FOLIC ACID, WITH HOMOCYSTEINE IN PATIENTS WITH ISCHEMIC STROKE

Author(s)

MONSHI KARIMI ALIREZA | MOHTADI NIA JAVAD | FARHOODI MAHDI | AREF HOSSEINI SAYED RAFI | Issue Writer Certificate

Keywords

STROKEQ2

ISCHEMIAQ2

VITAMIN B12Q2

FOLIC ACIDQ2

HOMOCYSTEINEQ2

SMOKINGQ3

Abstract

Background and Objectives: HOMOCYSTEINE has been proposed as a potential risk factor for atherosclerosis. Numerous factors increase the level of HOMOCYSTEINE, among which is VITAMIN B12 and FOLIC ACID deficiency and SMOKING. The aim of the present study was to study the relationship between SMOKING status, VITAMIN B12 and FOLIC ACID with HOMOCYSTEINE in patients with ischemic STROKE.Material and Methods: In a cross-sectional study through simple random sampling, 46 patients with ischemic STROKE aged 45-75 years admitted in neurology ward of Emam Khomeini hospital in Tabriz were recruited. Moreover, 46 healthy individuals with matched age and sex were studied. Blood sampling was performed in order to measure the levels of HOMOCYSTEINE, VITAMIN B12 and FOLIC ACID.Results: The mean serum HOMOCYSTEINE level was 18.68±1.53 mmol/L in the patient group which was significantly higher than that in the control group (9.96±0.19 mmol/L). Anthropometric profiles (weight and wrist circumstance) and body mass index were inversely correlated with the serum HOMOCYSTEINE level. Furthermore, significant difference was found in the mean number of exercise per week between the control (2.95±0.50) and patient groups (0.42±0.21). In addition, the mean years of cigarette SMOKING in control group (0.36±0.26) was significantly less than that in the patient group (9.67±1.67).Conclusion: Insufficient intake of FOLIC ACID and VITAMIN B12 along with cigarette SMOKING increase the serum level of HOMOCYSTEINE and subsequently increase probability of ischemic STROKE.

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APA: Copy

MONSHI KARIMI, ALIREZA, MOHTADI NIA, JAVAD, FARHOODI, MAHDI, & AREF HOSSEINI, SAYED RAFI. (2011). RELATIONSHIP BETWEEN SMOKING STATUS, VITAMIN B12 AND FOLIC ACID, WITH HOMOCYSTEINE IN PATIENTS WITH ISCHEMIC STROKE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 33(2), 81-86. SID. https://sid.ir/paper/47407/en

Vancouver: Copy

MONSHI KARIMI ALIREZA, MOHTADI NIA JAVAD, FARHOODI MAHDI, AREF HOSSEINI SAYED RAFI. RELATIONSHIP BETWEEN SMOKING STATUS, VITAMIN B12 AND FOLIC ACID, WITH HOMOCYSTEINE IN PATIENTS WITH ISCHEMIC STROKE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;33(2):81-86. Available from: https://sid.ir/paper/47407/en

IEEE: Copy

ALIREZA MONSHI KARIMI, JAVAD MOHTADI NIA, MAHDI FARHOODI, and SAYED RAFI AREF HOSSEINI, “RELATIONSHIP BETWEEN SMOKING STATUS, VITAMIN B12 AND FOLIC ACID, WITH HOMOCYSTEINE IN PATIENTS WITH ISCHEMIC STROKE,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 33, no. 2, pp. 81–86, 2011, [Online]. Available: https://sid.ir/paper/47407/en

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