STUDY OF CORRELATION BETWEEN SERUM LEPTIN LEVELS AND BODY COMPOSITION IN HEALTHY OBESE AND NON-OBESE WOMEN

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OSTAD RAHIMI A.R.; ZARGHAMI N.A.; MORADI TALA; RAF RAF M.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2007 | Volume:29 | Issue:2 Page(s): 15-20

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Title

STUDY OF CORRELATION BETWEEN SERUM LEPTIN LEVELS AND BODY COMPOSITION IN HEALTHY OBESE AND NON-OBESE WOMEN

Author(s)

OSTAD RAHIMI A.R. | ZARGHAMI N.A. | MORADI TALA | RAF RAF M. | Issue Writer Certificate

Keywords

LEPTINQ2

BODY MASS INDEXQ2

FAT MASSQ3

FREE FAT MASSQ3

WHRQ3

Abstract

Background and objectives: LEPTIN, the product of the ob gene, is a hormone secreted by adipocytes, and results in a decrease in food intake an increase in energy expenditure via hypothalamic interactions. In animal models, obesity can be caused by LEPTIN deficiency or dysfunction of hypothalamic LEPTIN receptor. The aim of this study was to examin the relation between serum LEPTIN levels and body composition. Materials and Methods: In this study, we measured serum concentration of LEPTIN in 51 normal weight subjects (BMI<25 kg/m2) and 50 obese subjects (BMI³25) by ELISA. BMI was defined as the weight in kilogram divided by the square of height in meters and body composition was determined by bioimpedance analyzer. Results: The mean (±SE) serum LEPTIN concentrations were 17.5±0.81 ng per milliliter in obese subjects and 4.9±0.55 ng per milliliter in the normal weight women (p<0.0005). There were a strong positive correlation between serum LEPTIN concentration and body FAT MASS (r=0.53) and BMI (r=0.41) in obese women and lean body mass was inversely related to LEPTIN concentration in normal weight subjects (r=-0.28). Significant relation between LEPTIN and WHR neither in obese nor in normal weight group was not observed. Conclusion: We conclude that circulating LEPTIN raised continuously with increasing adiposity and body FAT MASS is the main predictor of serum LEPTIN concentration.

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APA: Copy

OSTAD RAHIMI, A.R., ZARGHAMI, N.A., MORADI, TALA, & RAF RAF, M.. (2007). STUDY OF CORRELATION BETWEEN SERUM LEPTIN LEVELS AND BODY COMPOSITION IN HEALTHY OBESE AND NON-OBESE WOMEN. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 29(2), 15-20. SID. https://sid.ir/paper/47579/en

Vancouver: Copy

OSTAD RAHIMI A.R., ZARGHAMI N.A., MORADI TALA, RAF RAF M.. STUDY OF CORRELATION BETWEEN SERUM LEPTIN LEVELS AND BODY COMPOSITION IN HEALTHY OBESE AND NON-OBESE WOMEN. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;29(2):15-20. Available from: https://sid.ir/paper/47579/en

IEEE: Copy

A.R. OSTAD RAHIMI, N.A. ZARGHAMI, TALA MORADI, and M. RAF RAF, “STUDY OF CORRELATION BETWEEN SERUM LEPTIN LEVELS AND BODY COMPOSITION IN HEALTHY OBESE AND NON-OBESE WOMEN,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 29, no. 2, pp. 15–20, 2007, [Online]. Available: https://sid.ir/paper/47579/en

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