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Information Journal Paper

Title

STUDY OF PAI-1-675 4G/5G POLYMORPHISM AMONG PATIENTS WITH BREAST CANCER FROM NORTH WEST OF IRAN

Pages

  81-85

Abstract

 Background: Previous studies have shown the association of genetic factors such as PAI-1 4G/5G POLYMORPHISM with susceptibility to BREAST CANCER patients. The aim of this study was to investigate the effect of this POLYMORPHISM in BREAST CANCER patients from North West of Iran. Methods: 160 BREAST CANCER patients and 160 healthy individuals were selected. Peripheral blood-DNA samples were taken and used for PCR amplification using the allele specific primers. Results: Based on molecular studies, all patients and control group were divided into three genotypes 4G/4G, 4G/5G and 5G/5G. Genotype distribution between patients (11. 25%, 71. 25% and 17. 50%, respectively) and controls (10. 62%, 71. 87% and 17. 50%, respectively). Additionally, the frequencies of the 4G and 5G alleles between patients (46. 87% and 53. 12%, respectively) and control group (46. 56% and 53. 43%, respectively). Conclusion: The genotypic and allelic frequencies of PAI-1 4G/5G POLYMORPHISM showed no significant difference between BREAST CANCER patients and control individuals in this cohort.

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    APA: Copy

    YOUNESI, MAHDIEH, HOSSEINPOUR FEIZI, MOHAMMADALI, & POULADI, NASSER. (2018). STUDY OF PAI-1-675 4G/5G POLYMORPHISM AMONG PATIENTS WITH BREAST CANCER FROM NORTH WEST OF IRAN. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 39(6 ), 81-85. SID. https://sid.ir/paper/47598/en

    Vancouver: Copy

    YOUNESI MAHDIEH, HOSSEINPOUR FEIZI MOHAMMADALI, POULADI NASSER. STUDY OF PAI-1-675 4G/5G POLYMORPHISM AMONG PATIENTS WITH BREAST CANCER FROM NORTH WEST OF IRAN. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;39(6 ):81-85. Available from: https://sid.ir/paper/47598/en

    IEEE: Copy

    MAHDIEH YOUNESI, MOHAMMADALI HOSSEINPOUR FEIZI, and NASSER POULADI, “STUDY OF PAI-1-675 4G/5G POLYMORPHISM AMONG PATIENTS WITH BREAST CANCER FROM NORTH WEST OF IRAN,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 39, no. 6 , pp. 81–85, 2018, [Online]. Available: https://sid.ir/paper/47598/en

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