SERUM VITAMIN E STATUS IN WOMEN USERS OF LOW-DOSE ORAL CONTRACEPTIVES AND IN POSTMENOPAUSAL WOMEN TAKING HORMONE REPLACEMENT THERAPY

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MAHDAVI R.; RAFRAF M.; RASHIDI M.R.

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Journal: PHARMACEUTICAL SCIENCES Year:2005 | Volume:- | Issue:1 Page(s): 1-8

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Title

SERUM VITAMIN E STATUS IN WOMEN USERS OF LOW-DOSE ORAL CONTRACEPTIVES AND IN POSTMENOPAUSAL WOMEN TAKING HORMONE REPLACEMENT THERAPY

Author(s)

MAHDAVI R. | RAFRAF M. | RASHIDI M.R. | Issue Writer Certificate

Keywords

VITAMIN EQ2

ORAL CONTRACEPTIVESQ2

HORMONE REPLACEMENT THERAPYQ2

Abstract

The objective of this study was to investigate the serum VITAMIN E status and value of VITAMIN E / TC and VITAMIN E / LDL-C in women who use low-dose ORAL CONTRACEPTIVES (OCs) containing 0.15 mg levonorgestrol and 0.03 mg ethinyl estradiol and also in postmenopausal women who take HORMONE REPLACEMENT THERAPY (HRT). One hundred – thirty nine healthy non pregnant–non lactating women with a mean age of 32 years old (70 were OCs users and 69 were non-OCs users) and sixty healthy postmenopausal women, with a mean age of 51 years old (30 were under HRT and 30 were untreated) were studied using biochemical procedures (measurement of serum VITAMIN E and lipids levels), anthropometric measurements(weight and height)and interview with the subjects. No significant difference was found between either OCs and non-OCs users or HRT and non-HRT groups in terms of mean body mass index (BMI), and dietary intakes of VITAMIN E, total fat and total fiber. There were no significant differences between serum VITAMIN E levels and the mean value of VITAMIN E/TC in either OCs-users and non-OCs users or HRT and non-HRT groups. The mean value of VITAMIN E/LDL-C in HRT group was significantly higher than that of non-HRT group (7.13±3.48 vs 5.32±2.10, p<0.01). There was no significant difference between mean value of VITAMIN E/LDL-C in OCs and non-OCs groups. As a conclusion, using low-dose OCs has not resulted in altered VITAMIN E metabolism in OCs-Users compared to non-OCs Users. However, in postmenopausal women, taking HRT have had positive effect on serum VITAMIN E/LDL-C ratio, which is suitable indicator of VITAMIN E status.

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APA: Copy

MAHDAVI, R., RAFRAF, M., & RASHIDI, M.R.. (2005). SERUM VITAMIN E STATUS IN WOMEN USERS OF LOW-DOSE ORAL CONTRACEPTIVES AND IN POSTMENOPAUSAL WOMEN TAKING HORMONE REPLACEMENT THERAPY. PHARMACEUTICAL SCIENCES, -(1), 1-8. SID. https://sid.ir/paper/48420/en

Vancouver: Copy

MAHDAVI R., RAFRAF M., RASHIDI M.R.. SERUM VITAMIN E STATUS IN WOMEN USERS OF LOW-DOSE ORAL CONTRACEPTIVES AND IN POSTMENOPAUSAL WOMEN TAKING HORMONE REPLACEMENT THERAPY. PHARMACEUTICAL SCIENCES[Internet]. 2005;-(1):1-8. Available from: https://sid.ir/paper/48420/en

IEEE: Copy

R. MAHDAVI, M. RAFRAF, and M.R. RASHIDI, “SERUM VITAMIN E STATUS IN WOMEN USERS OF LOW-DOSE ORAL CONTRACEPTIVES AND IN POSTMENOPAUSAL WOMEN TAKING HORMONE REPLACEMENT THERAPY,” PHARMACEUTICAL SCIENCES, vol. -, no. 1, pp. 1–8, 2005, [Online]. Available: https://sid.ir/paper/48420/en

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