FORMULATION, ASSESSMENT AND COMPARSION OF TWO ANTIPERSPIRANTS CONTAINING ALUMINUM CHLOROHYDRATE AND GALLIC ACID

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GHARAVI MANOUCHEHR; SHOKRAEI K.

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Journal: PHARMACEUTICAL SCIENCES Year:2000 | Volume:- | Issue:3 Page(s): 63-68

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Title

FORMULATION, ASSESSMENT AND COMPARSION OF TWO ANTIPERSPIRANTS CONTAINING ALUMINUM CHLOROHYDRATE AND GALLIC ACID

Author(s)

GHARAVI MANOUCHEHR | SHOKRAEI K. | Issue Writer Certificate

Keywords

ANTIPERSPIRANTSQ3

ALUMINUM CHOLOROYHDRATEQ3

GALLIC ACIDQ3

Abstract

Background: recently ANTIPERSPIRANTS constitue' one of main products for personal care used by all strata of the population. In general astringent agents with relative blocking of the duct of eccrine glands decrease the rate of perspiration and malodors. In this study aluminum cholorohydrate (coded A) and GALLIC ACID (coded G) were used as active materials, veegum as viscosity modifier and glyceryl monostearate as oil phase.Methods: Emulsions were prepared with inversion method and final product was roll-on. For assessment of samples tests were carried out including: viscosity measurement, freeze & thaw, pH measurement and consumner panel test. Besides to evaluate effectiveness of the samples, difference in rate of perspiration before and after using the samples were determined gravimetrically.Results: Both samples were thixotrop and gravimetry test indicated that antiperspirant activity of sample A was 47% and sample G was 33%. These results were in good agreement with those of consumer panel test, and no irritation reaction was reported.Discussion: Veegum in these formulations conferred consistency, and physical stability. Sample A with antibacterial and deodorant effects was more suitable than sample G. Sample G was an acceptable antiperspirant, but it was susceptible to water and changing its color by oxidation. The gravimetry method proved to be a practical method to measure the rate of antiperspirant sample in ordinary conditions.

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APA: Copy

GHARAVI, MANOUCHEHR, & SHOKRAEI, K.. (2000). FORMULATION, ASSESSMENT AND COMPARSION OF TWO ANTIPERSPIRANTS CONTAINING ALUMINUM CHLOROHYDRATE AND GALLIC ACID. PHARMACEUTICAL SCIENCES, -(3), 63-68. SID. https://sid.ir/paper/48515/en

Vancouver: Copy

GHARAVI MANOUCHEHR, SHOKRAEI K.. FORMULATION, ASSESSMENT AND COMPARSION OF TWO ANTIPERSPIRANTS CONTAINING ALUMINUM CHLOROHYDRATE AND GALLIC ACID. PHARMACEUTICAL SCIENCES[Internet]. 2000;-(3):63-68. Available from: https://sid.ir/paper/48515/en

IEEE: Copy

MANOUCHEHR GHARAVI, and K. SHOKRAEI, “FORMULATION, ASSESSMENT AND COMPARSION OF TWO ANTIPERSPIRANTS CONTAINING ALUMINUM CHLOROHYDRATE AND GALLIC ACID,” PHARMACEUTICAL SCIENCES, vol. -, no. 3, pp. 63–68, 2000, [Online]. Available: https://sid.ir/paper/48515/en

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