ANTIDIABETIC EFFECT OF CITRULLUS COLOCYNTHIS FRUIT AQUEOUS EXTRACT ON PLASMA GLUCOSE LEVELS IN DIABETIC RABBITS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MAHDAVI R.; DASHTI N.; OSTAD RAHIMI A.R.; DELAZAR A.; REZAZADEH H.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: PHARMACEUTICAL SCIENCES Year:2005 | Volume:- | Issue:3 Page(s): 15-19

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,099

Download:

Cites:

Information Journal Paper

Title

ANTIDIABETIC EFFECT OF CITRULLUS COLOCYNTHIS FRUIT AQUEOUS EXTRACT ON PLASMA GLUCOSE LEVELS IN DIABETIC RABBITS

Author(s)

Keywords

CIRRUUUS COLOCYNTHISQ2

ANTIDIABETICQ2

DIABETIC RABBITSQ2

Abstract

OBJECTIVES: Citrullus colocynthis (Handal) is a medical plant have been used for the treatment of diabetes in Iran from a long time ago. METHODS: The ANTIDIABETIC effect of hydromethanolic (70%) extracts of Handal on the plasma glucose levels were investigated in DIABETIC RABBITS. The rabbits were randomly divided to 3 groups, the first group as a control the second and the third as a test 100 mg/kg and 200 mg/kg of extracts were administrated orally to group 2 and group3 for 6 days respectively.RESULTS: The first day, oral administration of 100 mg/kg of C. colocynthis, produced non significant reduction in plasma glucose levels after 2 and 6h and significant reduction after 12 h in comparison with the first group (p<0.05). Every 3 time, the dose of 200 mg/kg was due to significant blood glucose reduction in comparison with the control group. Mean blood glucose levels decreased in both test groups during the third and the fifth day of study, However, it was significant only in group 2 the fifth day (p<0.000) All the rabbits of group 3 died of diarrhea in the sixth day of experiment. CONCLUSIONT: he results suggest that although hydromethanolic extract of the pulp of C. colocynthis can decrease plasma glucose levels in DIABETIC RABBITS, further studies are necessary for finding the effective and safety dose.

Cites

No record.

References

اپیدمیولوژی دیابت قندی

Cite

APA: Copy

MAHDAVI, R., DASHTI, N., OSTAD RAHIMI, A.R., DELAZAR, A., & REZAZADEH, H.. (2005). ANTIDIABETIC EFFECT OF CITRULLUS COLOCYNTHIS FRUIT AQUEOUS EXTRACT ON PLASMA GLUCOSE LEVELS IN DIABETIC RABBITS. PHARMACEUTICAL SCIENCES, -(3), 15-19. SID. https://sid.ir/paper/48545/en

Vancouver: Copy

MAHDAVI R., DASHTI N., OSTAD RAHIMI A.R., DELAZAR A., REZAZADEH H.. ANTIDIABETIC EFFECT OF CITRULLUS COLOCYNTHIS FRUIT AQUEOUS EXTRACT ON PLASMA GLUCOSE LEVELS IN DIABETIC RABBITS. PHARMACEUTICAL SCIENCES[Internet]. 2005;-(3):15-19. Available from: https://sid.ir/paper/48545/en

IEEE: Copy

R. MAHDAVI, N. DASHTI, A.R. OSTAD RAHIMI, A. DELAZAR, and H. REZAZADEH, “ANTIDIABETIC EFFECT OF CITRULLUS COLOCYNTHIS FRUIT AQUEOUS EXTRACT ON PLASMA GLUCOSE LEVELS IN DIABETIC RABBITS,” PHARMACEUTICAL SCIENCES, vol. -, no. 3, pp. 15–19, 2005, [Online]. Available: https://sid.ir/paper/48545/en

Related Journal Papers