TREATMENT OF SKIN TUMORS WITH ELECTRO CHEMOTHERAPY

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ASILIAN ALI; MOMENI IMAN; BASIRI AKRAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Isfahan Medical School Year:2013 | Volume:31 | Issue:226 Page(s): 180-189

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Information Journal Paper

Title

TREATMENT OF SKIN TUMORS WITH ELECTRO CHEMOTHERAPY

Author(s)

ASILIAN ALI | MOMENI IMAN | BASIRI AKRAM | Issue Writer Certificate

Keywords

NEOPLASMQ3

PHARMACOTHERAPYQ3

ELECTROPORATIONQ2

ELECTRO CHEMOTHERAPYQ2

DRUG DELIVERY SYSTEMQ2

BLEOMYCINQ3

CISPLATINQ2

Abstract

Electro chemotherapy involves the application of chemotherapy followed by local electrical pulse around the tumor to increase drug delivery into tumor cells. ELECTROPORATION is used to increase drug absorbance only for medications whose transport is prevented by plasma membrane. Among all available medicines, BLEOMYCIN and CISPLATIN have been widely studied in pre-clinical and clinical trials. In-vitro observations revealed an increase in cytotoxicity of these drugs after the application of electrical pulses. In-vivo studies have suggested tumor ELECTROPORATION after local or systemic chemotherapy therapy (electro chemotherapy) as an effective antitumor treatment. This method has also been successfully used in treating primary tumors of cats, dogs, and horses. Pre-clinical research on several types of tumor has clarified the parameters resulting to the effective, local control of tumors. In human clinical trials, ELECTRO CHEMOTHERAPY has been an efficient method for treating advanced diseases with accessible malignant tumors of various types.

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APA: Copy

ASILIAN, ALI, MOMENI, IMAN, & BASIRI, AKRAM. (2013). TREATMENT OF SKIN TUMORS WITH ELECTRO CHEMOTHERAPY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 31(226), 180-189. SID. https://sid.ir/paper/50841/en

Vancouver: Copy

ASILIAN ALI, MOMENI IMAN, BASIRI AKRAM. TREATMENT OF SKIN TUMORS WITH ELECTRO CHEMOTHERAPY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2013;31(226):180-189. Available from: https://sid.ir/paper/50841/en

IEEE: Copy

ALI ASILIAN, IMAN MOMENI, and AKRAM BASIRI, “TREATMENT OF SKIN TUMORS WITH ELECTRO CHEMOTHERAPY,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 31, no. 226, pp. 180–189, 2013, [Online]. Available: https://sid.ir/paper/50841/en

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