DRUG RESISTANCE PATTERN OF CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM A REFERRAL BURN CENTER IN NORTHEAST OF IRAN

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Sarhaddi Nazanin; Dolatabadi Samaneh; AMEL JAMEHDAR SAEID

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Journal Paper

Paper Information

Journal: Medical Journal of Mashhad University of Medical Sciences Year:2016 | Volume:59 | Issue:1 Page(s): 1-8

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Title

DRUG RESISTANCE PATTERN OF CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM A REFERRAL BURN CENTER IN NORTHEAST OF IRAN

Author(s)

Sarhaddi Nazanin | Dolatabadi Samaneh | AMEL JAMEHDAR SAEID | Issue Writer Certificate

Keywords

ACINETOBACTER BAUMANNIIQ1

CARBAPENEM-RESISTANTQ1

MASHHADQ2

Abstract

Introduction: ACINETOBACTER BAUMANNII, an opportunistic gram negative bacteria, is a threat in hospital infections, especially in ICU wards due to the high survival ability and talent to get different antibiotic resistance. So far, there are few reports about sensitivity patterns of multi-drug resistant ACINETOBACTER BAUMANNII (MDR), especially carbapenem resistance from various hospitals in MASHHAD, Iran.Methods: In this study 54 strains of MDR from referral burn unit of Imam Reza hospital in MASHHAD were collected during October to March 2013. Sensitivity pattern to antibiotics was determined by Kirby-Bauer method for each isolate. Frequency of various genes responsible for resistance to carbapenem was studied for each isolte by PCR method.Results: The rate of resistance to tested antibiotics was more than 95%. In addition, this study showed the high prevalence of blaVIM, blaIMP, blaTEM, blaADC, OXA-Like23, OXA-Like24, OXA-Like51, OXA-Like58 and ISAba1 genes, that mediated resistance to betalactam antibiotics.Conclusion: These results indicate that all isolates were resistant to betalactam antibiotics. These results suggest more study on rational usage of carbapenems for treatment of infections by ACINETOBACTER BAUMANNII.

Cites

Prevalence of IMP and SPM Genes in Clinical Isolates of Carbapenem Resistant Acinetobacter baumannii in Educational Hospitals of Sari, Iran

References

ISOLATION AND GENETIC CHARACTERIZATION OF METALLO-β-LACTAMASE AND CARBAPENAMASE PRODUCING STRAINS OF ACINETOBACTER BAUMANNII FROM PATIENTS AT TEHRAN HOSPITALS

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APA: Copy

Sarhaddi, Nazanin, Dolatabadi, Samaneh, & AMEL JAMEHDAR, SAEID. (2016). DRUG RESISTANCE PATTERN OF CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM A REFERRAL BURN CENTER IN NORTHEAST OF IRAN. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 59(1), 1-8. SID. https://sid.ir/paper/51541/en

Vancouver: Copy

Sarhaddi Nazanin, Dolatabadi Samaneh, AMEL JAMEHDAR SAEID. DRUG RESISTANCE PATTERN OF CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM A REFERRAL BURN CENTER IN NORTHEAST OF IRAN. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;59(1):1-8. Available from: https://sid.ir/paper/51541/en

IEEE: Copy

Nazanin Sarhaddi, Samaneh Dolatabadi, and SAEID AMEL JAMEHDAR, “DRUG RESISTANCE PATTERN OF CARBAPENEM-RESISTANT ACINETOBACTER BAUMANNII ISOLATED FROM A REFERRAL BURN CENTER IN NORTHEAST OF IRAN,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 59, no. 1, pp. 1–8, 2016, [Online]. Available: https://sid.ir/paper/51541/en

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