ISLET CELL ANTIBODIES (ICA) ASSAY IN TYPE I DIABETIC PATIENTS AND THEIR SIBLINGS

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MOUSAVI Z.; KHAZAEI M.H.; BARADARAN H.; BAHARI A.A.

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Paper Information

Journal: Medical Journal of Mashhad University of Medical Sciences Year:2001 | Volume:44 | Issue:72 Page(s): 61-66

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Title

ISLET CELL ANTIBODIES (ICA) ASSAY IN TYPE I DIABETIC PATIENTS AND THEIR SIBLINGS

Author(s)

MOUSAVI Z. | KHAZAEI M.H. | BARADARAN H. | BAHARI A.A. | Issue Writer Certificate

Keywords

DIABETESQ3

MELLITUS TYPE IQ4

ISLET CELL ANTIBODIES (ICA)Q4

Abstract

Prevention of type I DIABETES mellitus is appreciated recently. Multiple immunological markers were used for diagnosis and prediction of DIABETES mellitus (Type I). Among them, islet cell antibodies (ICA) in the circulation are the most important. During 2 years newly diagnosed type I DIABETES mellitus (group A) who adminted to the endocrine department or private clinics reruited in the study. Serum ICA were measured in this patients and their siblings (group B) and normal persons (group C) using immumo fluorescent assay (IFA). Group A was included 54 patients (24 male, 30 female and median age 15.9±8.2 year). Group B was included 79 persons (38 male and 41 female, median age 14±7 year) and control group was included 42 persons (22 male, 20 female and median age 19±6 year). Prevalence of ICA (Titer > 1/16) was 74.1%, 16.4% and 0% in groups A, B, C, respectively.Sensitivity and specificity of IFA method for ICA detection was 68.8% are 100% respectively. Predictive value of ICA for identification of high risk (ICA first - degree relative 100M patients is significant).

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APA: Copy

MOUSAVI, Z., KHAZAEI, M.H., BARADARAN, H., & BAHARI, A.A.. (2001). ISLET CELL ANTIBODIES (ICA) ASSAY IN TYPE I DIABETIC PATIENTS AND THEIR SIBLINGS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 44(72), 61-66. SID. https://sid.ir/paper/51767/en

Vancouver: Copy

MOUSAVI Z., KHAZAEI M.H., BARADARAN H., BAHARI A.A.. ISLET CELL ANTIBODIES (ICA) ASSAY IN TYPE I DIABETIC PATIENTS AND THEIR SIBLINGS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2001;44(72):61-66. Available from: https://sid.ir/paper/51767/en

IEEE: Copy

Z. MOUSAVI, M.H. KHAZAEI, H. BARADARAN, and A.A. BAHARI, “ISLET CELL ANTIBODIES (ICA) ASSAY IN TYPE I DIABETIC PATIENTS AND THEIR SIBLINGS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 44, no. 72, pp. 61–66, 2001, [Online]. Available: https://sid.ir/paper/51767/en

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