THE COMPARISON OF QUANTITATIVE 8 AND 24 HOUR URINE PROTEIN SAMPLES FOR DIAGNOSIS OF PREECLAMPSIA

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MOHAMMAD JAFARI R.; NAJAFIAN M.; SAVADDAR F.; CHERAGHI B.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2011 | Volume:54 | Issue:1 Page(s): 19-24

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Title

THE COMPARISON OF QUANTITATIVE 8 AND 24 HOUR URINE PROTEIN SAMPLES FOR DIAGNOSIS OF PREECLAMPSIA

Author(s)

MOHAMMAD JAFARI R. | NAJAFIAN M. | SAVADDAR F. | CHERAGHI B. | Issue Writer Certificate

Keywords

GOLD STANDARDQ3

PREECLAMPSIAQ3

PROTEINURIAQ4

Abstract

Introduction: Objectives: PREECLAMPSIA, clinically recognized by gestational hypertension with PROTEINURIA, occurs after 20 weeks' gestation is a leading cause of maternal and perinatal morbidity and mortality. Early diagnosis to prevent maternal and fetal complications is important. The GOLD STANDARD for PROTEINURIA, is a 24-hour urine sample for total protein. The purpose of this study was to compare the urine protein in the 8 –hour Sample with the 24-hour Sample Urine Profein to diagnose of PREECLAMPSIA.Materials and Methods: The study population included 76 in patients with hypertensive disorders of pregnancyduring 2009 and 2010. Patient's urine was collected over 24 hours with the first 8 hours, next 16 hours, in separate containers. The urine volume and total protein and creatinine levels were measured in the 8 and 24 hour samples. The results of 8 and 24-hour Sample were compared by useing of SPSS software Win PePi 1.45. The correlation between 8 and 24-hour tests was evaluated using Pearson and Spearman correlation coefficients. Of the 76 patients 18 cases had no PROTEINURIA, 53 had mild PROTEINURIA and 5 had severe pro-teinuria.Results: protein values for the first 8 hour sample have high correlation with the entire 24 hour sample for patients with mild (p<0.001,r=0.87),severe disease (p<0. 001 ,r=0.9). In cases with no proteinurea moderate correlation was found (P<0.001, r=0.59).Conclusion: The 8-hour sample correlates with the 24-hour sample for patients with no PROTEINURIA (p<0.001), mild PROTEINURIA (p<0.001) and severe PROTEINURIA (p<0.001).

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APA: Copy

MOHAMMAD JAFARI, R., NAJAFIAN, M., SAVADDAR, F., & CHERAGHI, B.. (2011). THE COMPARISON OF QUANTITATIVE 8 AND 24 HOUR URINE PROTEIN SAMPLES FOR DIAGNOSIS OF PREECLAMPSIA. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 54(1), 19-24. SID. https://sid.ir/paper/51888/en

Vancouver: Copy

MOHAMMAD JAFARI R., NAJAFIAN M., SAVADDAR F., CHERAGHI B.. THE COMPARISON OF QUANTITATIVE 8 AND 24 HOUR URINE PROTEIN SAMPLES FOR DIAGNOSIS OF PREECLAMPSIA. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;54(1):19-24. Available from: https://sid.ir/paper/51888/en

IEEE: Copy

R. MOHAMMAD JAFARI, M. NAJAFIAN, F. SAVADDAR, and B. CHERAGHI, “THE COMPARISON OF QUANTITATIVE 8 AND 24 HOUR URINE PROTEIN SAMPLES FOR DIAGNOSIS OF PREECLAMPSIA,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 54, no. 1, pp. 19–24, 2011, [Online]. Available: https://sid.ir/paper/51888/en

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