ASSESSMENT OF THE RELATION BETWEEN HYPOTHYROIDISM & SERUM LEVEL OF FERRITIN IN β THALASSEMIA PATIENTS

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ZENDEHBAD A.; MIRBEHBAHANI N.B.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2009 | Volume:52 | Issue:3 Page(s): 123-128

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Title

ASSESSMENT OF THE RELATION BETWEEN HYPOTHYROIDISM & SERUM LEVEL OF FERRITIN IN β THALASSEMIA PATIENTS

Author(s)

ZENDEHBAD A. | MIRBEHBAHANI N.B. | Issue Writer Certificate

Keywords

FERRITINQ3

MAJOR THALASSEMIAQ3

THYROID FUNCTIONQ3

Abstract

Introduction: b-thalassemia Major is one of the most common diseases in Iran especially in Golestan province. Blood transfusion has many important complications such as endocrine disorders & Hypothyriodism which can result in disability & untimely mortality. This study was designed to determine the association between Hypothyroidism & serum level of FERRITIN in these patients. Materials and Methods: This study was performed on all patients in thalassemia center of Gorgan (n=185) with age range of 1-37 years. During five years, level of FERRITIN & T3, T4, TSH were measured every three & 12 months respectively. Data were analyzed using SPSS software.Results: Thirty patients had hypothyroidism. Mean age was 17.8 years & male/female ratio was 1. Five patients were under the age of 10. The average level of FERRITIN at the onset of complication was 2528.400±2157.300 ng/ml. Serum level of FERRITIN in hypothyroidism, had shown a significant difference in comparison to non-hypothyroid patients (p<0.05).Conclusion: This study showed that to prevent hypothyroidism in MAJOR THALASSEMIA, we could start clinical & para-clinical studies¸ such as checking serum level of FERRITIN. Although endocrine abnormalities are usually sought in patients over 10 years of age, we recommend starting the endocrine screening at age 5 since we had 5 patients under the age of ten with these abnormalities.

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APA: Copy

ZENDEHBAD, A., & MIRBEHBAHANI, N.B.. (2009). ASSESSMENT OF THE RELATION BETWEEN HYPOTHYROIDISM & SERUM LEVEL OF FERRITIN IN β THALASSEMIA PATIENTS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 52(3), 123-128. SID. https://sid.ir/paper/51909/en

Vancouver: Copy

ZENDEHBAD A., MIRBEHBAHANI N.B.. ASSESSMENT OF THE RELATION BETWEEN HYPOTHYROIDISM & SERUM LEVEL OF FERRITIN IN β THALASSEMIA PATIENTS. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;52(3):123-128. Available from: https://sid.ir/paper/51909/en

IEEE: Copy

A. ZENDEHBAD, and N.B. MIRBEHBAHANI, “ASSESSMENT OF THE RELATION BETWEEN HYPOTHYROIDISM & SERUM LEVEL OF FERRITIN IN β THALASSEMIA PATIENTS,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 52, no. 3, pp. 123–128, 2009, [Online]. Available: https://sid.ir/paper/51909/en

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