STUDYING THE INHIBITORY EFFECT OF SAFFRON EXTRACT ON ADENOCARCINOMA OF COLON CELL LINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHOSRAVI AHMAD; FARID HOSSEINI REZA; JABARI AZAD FARAHZAD; YOUSEFZADEH HADIS; MOGHIMAN TOKTAM; VAEZ TABASI MOHAMMAD; TAVAKKOL AFSHARI JALIL

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Medical Journal of Mashhad University of Medical Sciences Year:2013 | Volume:56 | Issue:5 Page(s): 283-288

Download Full-Text

Persian Verion

View:

1,009

Download:

Cites:

Information Journal Paper

Title

STUDYING THE INHIBITORY EFFECT OF SAFFRON EXTRACT ON ADENOCARCINOMA OF COLON CELL LINE

Author(s)

Keywords

ATTENTIONQ3

DEFICIT HYPERACTIVITY DISORDERQ2

EPILEPSYQ2

EPIDEMIOLOGYQ2

Abstract

Introduction: We aimed to evaluate the antigenotoxic and cytotoxic effects of saffron as an endemic plant in our regionMaterials and Methods: Human gastric adenocarcinomatous cells (AGS) and colon cells were cultured in Dulbecco's modified Eagle's medium (DMEM) containing 10% FBS under standard conditions at 37°C in a 5% CO2-humidified incubator. The 2×105 cells in 200ul of complete medium were introduced to each well. Then MTT assay was used to measure the cellular changes for 200, 400, 800, 1200 and 2000 µg to ml extract in three studied cell lines AGS, HT125 and L929. Results: The L929 cells showed minor changes during the first 24 and 48 hours with extract concentrations of 2000 and 1600, respectively. But during the 72-hour interval significant changes in morphology took place in the same concentrations. While the decrease in AGS cells was more obvious, in the concentration of 2000, the live cell population reduced to 45%. No significant result was obtained in morphology and MTT test for HT125 cells.Conclusion: This study results support the increasing evidence that naturally occurring saffron extract may have an important role in cancer chemoprevention.

Cites

No record.

References

No record.

Cite

APA: Copy

KHOSRAVI, AHMAD, FARID HOSSEINI, REZA, JABARI AZAD, FARAHZAD, YOUSEFZADEH, HADIS, MOGHIMAN, TOKTAM, VAEZ TABASI, MOHAMMAD, & TAVAKKOL AFSHARI, JALIL. (2013). STUDYING THE INHIBITORY EFFECT OF SAFFRON EXTRACT ON ADENOCARCINOMA OF COLON CELL LINE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 56(5), 283-288. SID. https://sid.ir/paper/52082/en

Vancouver: Copy

KHOSRAVI AHMAD, FARID HOSSEINI REZA, JABARI AZAD FARAHZAD, YOUSEFZADEH HADIS, MOGHIMAN TOKTAM, VAEZ TABASI MOHAMMAD, TAVAKKOL AFSHARI JALIL. STUDYING THE INHIBITORY EFFECT OF SAFFRON EXTRACT ON ADENOCARCINOMA OF COLON CELL LINE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;56(5):283-288. Available from: https://sid.ir/paper/52082/en

IEEE: Copy

AHMAD KHOSRAVI, REZA FARID HOSSEINI, FARAHZAD JABARI AZAD, HADIS YOUSEFZADEH, TOKTAM MOGHIMAN, MOHAMMAD VAEZ TABASI, and JALIL TAVAKKOL AFSHARI, “STUDYING THE INHIBITORY EFFECT OF SAFFRON EXTRACT ON ADENOCARCINOMA OF COLON CELL LINE,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 56, no. 5, pp. 283–288, 2013, [Online]. Available: https://sid.ir/paper/52082/en

Related Journal Papers