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Information Journal Paper

Title

THE EFFECTS OF AQUEOUS EXTRACT FROM TEUCRIUM POLIUM L. ON RAT GASTRIC MOTILITY IN BASAL AND VAGAL-STIMULATED CONDITIONS

Pages

  60-65

Abstract

 ObjectiveThe aim of this study was to investigate the effects of aqueous extract from Teucrium polium L. on rat GASTRIC MOTILITY in basal and vagal stimulated conditions. Materials and MethodsTwenty four Wister rats (weighing 200-250g) were randomly divided in to groups of 12 as case and control. Animals were anesthetized by sodium thiopental (50 mg/kg, ip) and tracheostomy, laparatomy and gastrodeodenostomy were done for each rat. Aqueous extract of the plant was prepared by maceration and 1ml of 20, 40 and 80mg/kg doses were introduced into he stomach of each rat in case group and the same volume of saline was used in control group. GASTRIC MOTILITY was measured by pressure transducer.The results were analyzed by t-test and multivariate analysis and p<0.05 was considered to be significant.ResultsT.polium aqueous extract has decreased frequency of contraction in case vs control group in both conditions, but the intragastric pressure decreased in case group, although did not have insignificant encompassing with control group. T.polium aqueous extract has got effects on contraction frequency, showding time-response manner only in basal condition. Its effects on intragastric pressure in basal condition in presence of 20 mg/kg and in vagal stimulation in presence of 40 mg/kg dose of the extract were time- response. Intragastric pressure in vagal stimulation was dose dependent, but contraction frequency was not dose dependent, in both conditions.ConclusionIntragastric pressure with 3 different doses of aqueous extract of T.poliumin control and case groups had insignificant difference in two conditions, but the frequency of contraction significantly decreased in both conditions.

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    APA: Copy

    NIAZMAND, S., HAJIZADE, M., & KESHAVARZIPOUR, T.. (2007). THE EFFECTS OF AQUEOUS EXTRACT FROM TEUCRIUM POLIUM L. ON RAT GASTRIC MOTILITY IN BASAL AND VAGAL-STIMULATED CONDITIONS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 10(1 (33)), 60-65. SID. https://sid.ir/paper/52425/en

    Vancouver: Copy

    NIAZMAND S., HAJIZADE M., KESHAVARZIPOUR T.. THE EFFECTS OF AQUEOUS EXTRACT FROM TEUCRIUM POLIUM L. ON RAT GASTRIC MOTILITY IN BASAL AND VAGAL-STIMULATED CONDITIONS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2007;10(1 (33)):60-65. Available from: https://sid.ir/paper/52425/en

    IEEE: Copy

    S. NIAZMAND, M. HAJIZADE, and T. KESHAVARZIPOUR, “THE EFFECTS OF AQUEOUS EXTRACT FROM TEUCRIUM POLIUM L. ON RAT GASTRIC MOTILITY IN BASAL AND VAGAL-STIMULATED CONDITIONS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 10, no. 1 (33), pp. 60–65, 2007, [Online]. Available: https://sid.ir/paper/52425/en

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