IMPACT OF CALCIUM–VITAMIN D CO-SUPPLEMENTATION ON GLYCAEMIC CONTROL, INFLAMMATION AND OXIDATIVE STRESS IN GESTATIONAL DIABETES: A PARALLEL STUDY

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SADEGHIAN MEHDI; ASEMI ZATOLLAH; KARAMALI MARYAM; SANEEI PARVANEH; ESMAILLZADEH AHMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Diabetes and Metabolism Year:2015 | Volume:15 | Issue:1 Page(s): 53-65

Download Full-Text

Persian Verion

View:

1,020

Download:

Cites:

Information Journal Paper

Title

IMPACT OF CALCIUM–VITAMIN D CO-SUPPLEMENTATION ON GLYCAEMIC CONTROL, INFLAMMATION AND OXIDATIVE STRESS IN GESTATIONAL DIABETES: A PARALLEL STUDY

Author(s)

Keywords

GESTATIONAL DIABETES

CALCIUM SUPPLEMENTATION

VITAMIN D

METABOLIC PROFILE

Abstract

Background: This study was designed to assess the effects of calcium and VITAMIN D supplementation on the metabolic status of pregnant women with GESTATIONAL DIABETES mellitus (GDM).Methods: This randomized placebo-controlled trial was performed at maternity clinics affiliated to Kashan University of Medical Sciences, Kashan, Iran. Participants were 56 women with GDM at 24–28 weeks gestation (18 to 40 years of age). Subjects were randomly assigned to receive calcium plus VITAMIN D supplements or placebo. All study participants were blinded to group assignment.Individuals in the calcium–vita- min D group (n=28) received 1, 000 mg calcium per day and a 50, 000 U VITAMIN D3 pearl twice during the study (at study baseline and on day 21 of the intervention), and those in the placebo group (n=28) received two placebos at the mentioned times.Fasting blood samples were taken at study baseline and after 6 weeks of intervention.Results: The study was completed by 51 participants (calcium–vitamin D n=25, placebo n=26).However, as the analysis was based on an intention-to-treat approach, all 56 women with GDM (28 in each group) were included in the final analysis. After the administration of calcium plus VITAMIN D supplements, we observed a significant reduction in fasting plasma glucose (p<0.001), serum insulin levels (p=0.02) and HOMA-IR (p=0.001) and a significant increase in QUICKI (p=0.003) compared with placebo. In addition, a significant reduction in serum LDL-cholesterol (P=0.02) and total cholesterol: HDL-cholesterol ratio (p=0.003) and a significant elevation in HDL-cholesterol levels (p=0.01) was seen after intervention in the calcium–vitamin D group compared with placebo.In addition, calcium plus VITAMIN D supplementation resulted in a significant increase in GSH (p =0.03) and prevented a rise in MDA levels (p=0.03) compared with placebo.Conclusion: Calcium plus VITAMIN D supplementation in women with GDM had beneficial effects on their METABOLIC PROFILE.

Cites

No record.

References

No record.

Cite

APA: Copy

SADEGHIAN, MEHDI, ASEMI, ZATOLLAH, KARAMALI, MARYAM, SANEEI, PARVANEH, & ESMAILLZADEH, AHMAD. (2015). IMPACT OF CALCIUM–VITAMIN D CO-SUPPLEMENTATION ON GLYCAEMIC CONTROL, INFLAMMATION AND OXIDATIVE STRESS IN GESTATIONAL DIABETES: A PARALLEL STUDY. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 15(1), 53-65. SID. https://sid.ir/paper/53919/en

Vancouver: Copy

SADEGHIAN MEHDI, ASEMI ZATOLLAH, KARAMALI MARYAM, SANEEI PARVANEH, ESMAILLZADEH AHMAD. IMPACT OF CALCIUM–VITAMIN D CO-SUPPLEMENTATION ON GLYCAEMIC CONTROL, INFLAMMATION AND OXIDATIVE STRESS IN GESTATIONAL DIABETES: A PARALLEL STUDY. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2015;15(1):53-65. Available from: https://sid.ir/paper/53919/en

IEEE: Copy

MEHDI SADEGHIAN, ZATOLLAH ASEMI, MARYAM KARAMALI, PARVANEH SANEEI, and AHMAD ESMAILLZADEH, “IMPACT OF CALCIUM–VITAMIN D CO-SUPPLEMENTATION ON GLYCAEMIC CONTROL, INFLAMMATION AND OXIDATIVE STRESS IN GESTATIONAL DIABETES: A PARALLEL STUDY,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 15, no. 1, pp. 53–65, 2015, [Online]. Available: https://sid.ir/paper/53919/en

Related Journal Papers