CARCINOMA IN MULTINODULAR GOITER

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MAHZOUNI P.; KHARAZIYAN A.

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Journal Paper

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Journal: Yafteh Year:2001 | Volume:2 | Issue:6-7 Page(s): 21-23

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Information Journal Paper

Title

CARCINOMA IN MULTINODULAR GOITER

Author(s)

MAHZOUNI P. | KHARAZIYAN A. | Issue Writer Certificate

Keywords

MULTINODULAR GOITER

LATENT CARCINOMA

PAPILLARY CARCINOMA

Abstract

Enlargement of the thyroid, or goiter, is the most common manifestation of thyroid disease. MULTINODULAR GOITER can produce the most extreme thyroid enlargements and is more frequently mistaken for neoplastic involvement than any other form of thyroid disease. MULTINODULAR GOITER is a benign disease but foci of malignant changes may exist in it that can't be diagnosed by physical examination, ultrasonography or radioisotope scanning and only after removal of gland by surgery and pathologic examination is diagnosed. The object of this study is relative frequency evaluation of carcinoma in MULTINODULAR GOITER specimens that removed by surgery and sent for pathologic examination.Total and subtotal thyroidectomy specimens belonged to 278 Patients with previous MULTINODULAR GOITER diagvosis was evaluated. Specimens with malignant change foci have suspected positive and histologic type and malignant differentiation grade obtained. From 278 Specimens which were evaluated, 14 specimens had malignant changes associated with malt nodular goiter. Relative frequency of carcinoma in 8 evaluated pecimens was 5% in females and2.4% in males. The most frequent kind of carcinoma associated with maltinodular goiter was PAPILLARY CARCINOMA.MULTINODULAR GOITER disease can have malignant changes in the form of LATENT CARCINOMA which is diagnosed only after pathologic evaluation.

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