INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES

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EMAMI SEYED AHMAD; ZAMANAI TAGHIZADEH RABE SHAHRZAD; AHI ALI; MAHMOUDI MAHMOUD

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Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2012 | Volume:15 | Issue:2 Page(s): 787-791

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Title

INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES

Author(s)

EMAMI SEYED AHMAD | ZAMANAI TAGHIZADEH RABE SHAHRZAD | AHI ALI | MAHMOUDI MAHMOUD | Issue Writer Certificate

Keywords

ARTEMISIA

LEISHMANICIDAL ACTIVITY

LEISHMANIA MAJOR

MTT ASSAY

PROMASTIGOTE

Abstract

Objective(s): Annual incidence of cutaneous leishmaniasis is increasingly growing and development of the alternative drugs against it is a major concern. ARTEMISIA genus is a traditional medicinal plant in Iran. The aim of this study was to examine the LEISHMANICIDAL ACTIVITY of various Iranian ARTEMISIA species extracts.Materials and Methods: Different extracts were gathered from eleven Iranian ARTEMISIA species. Their leishmanicidal activIties against the growth of LEISHMANIA MAJOR (L. major) PROMASTIGOTEs were examined as the half maximal inhibitory concentration (lCso) using MTT ASSAY.Results: Obtained results showed that ethanol extracts especially those taken fromA. ciniformis, A. santolina and A. kulbadicahave the strongest effects.Conclusion: Looking for the effective leishmanicidal agents from natural resources in Iran, we found that the ethanol extract of collected ARTEMISIA species had significant effect on in vitro LEISHMANICIDAL ACTIVITY and may be suitable candidates in the treatment of leishmaniasis.

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APA: Copy

EMAMI, SEYED AHMAD, ZAMANAI TAGHIZADEH RABE, SHAHRZAD, AHI, ALI, & MAHMOUDI, MAHMOUD. (2012). INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 15(2), 787-791. SID. https://sid.ir/paper/578404/en

Vancouver: Copy

EMAMI SEYED AHMAD, ZAMANAI TAGHIZADEH RABE SHAHRZAD, AHI ALI, MAHMOUDI MAHMOUD. INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2012;15(2):787-791. Available from: https://sid.ir/paper/578404/en

IEEE: Copy

SEYED AHMAD EMAMI, SHAHRZAD ZAMANAI TAGHIZADEH RABE, ALI AHI, and MAHMOUD MAHMOUDI, “INHIBITORY ACTIVITY OF ELEVEN ARTEMISIA SPECIES FROM IRAN AGAINST LEISHMANIA MAJOR PARASITES,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 15, no. 2, pp. 787–791, 2012, [Online]. Available: https://sid.ir/paper/578404/en

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