EVALUATION OF NERIUM OLEANDER AQUEOUS EXTRACT EFFECT ON STAPHYLOCOCCUS AUREUSAND STAPHYLOCOCCUS EPIDERMIS

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HAMOUNNAVARD S.; BAHRAMI A.M.; RAZMJOU M.; ASADI SAMANI M.; HATAMI LAK M.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2013 | Volume:15 | Issue:1 Page(s): 46-54

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Title

EVALUATION OF NERIUM OLEANDER AQUEOUS EXTRACT EFFECT ON STAPHYLOCOCCUS AUREUSAND STAPHYLOCOCCUS EPIDERMIS

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Keywords

ANTIBACTERIAL EFFECTQ2

ANTIBIOTIC RESISTANCEQ2

NERIUM OLEANDERQ2

STAPHYLOCOCCUS AUREUSQ2

STAPHYLOCOCCUS EPIDERMISQ3

Abstract

Background and aims: ANTIBIOTIC RESISTANCE has paved the way for replacing conventional medications with herbal therapies that supposedly have less side- effects. The present study aimed to investigate the ANTIBACTERIAL EFFECT of NERIUM OLEANDER on strains of STAPHYLOCOCCUS AUREUSand STAPHYLOCOCCUS EPIDERMIS.Methods: In this experimental study, the aqueous extract effect of NERIUM OLEANDER's leaf and flower on STAPHYLOCOCCUS AUREUS and STAPHYLOCOCCUS EPIDERMIS was independently investigated through boiling at three 12.5, 25 and 50 mg/ml concentrations, in 20, 40 and 80ml by well diffusion and disk methods. Antibiogram test was performed on these two strains with three antibiotics, namely, oxitetracycline, erythromycin and penicillin. The diameter zone of inhibition was measured and the effect of extract was evaluated.Results: According to antibiogram test STAPHYLOCOCCUS AUREUS was sensitive to erythromycin, but resistant to oxitetracycline and penicillin.Staphylococcus epidermis was relatively resistant to erythromycin, but resistant to oxitetracycline and penicillin. STAPHYLOCOCCUS AUREUS was sensitive to 40 and 80 ml in 25 mg/ml concentration and all amounts of leaf extract in 50 mg/ml concentration. Butstaphylococcuy epiderm is showed no sensitirity to the mentioned concentrations. In all concentration adding the amount of extract from 20 to 80 ml, mean of diameter zone was increased. Leaf extract has more inhibitoty effect compare to flower extract.Conclusion: Regarding the fact that ANTIBIOTIC RESISTANCE is growing, the extract of NERIUM OLEANDERcould be used as an antibacterial compound for external application on wounds and removal of epidermal infections.

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APA: Copy

HAMOUNNAVARD, S., BAHRAMI, A.M., RAZMJOU, M., ASADI SAMANI, M., & HATAMI LAK, M.. (2013). EVALUATION OF NERIUM OLEANDER AQUEOUS EXTRACT EFFECT ON STAPHYLOCOCCUS AUREUSAND STAPHYLOCOCCUS EPIDERMIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 15(1), 46-54. SID. https://sid.ir/paper/58385/en

Vancouver: Copy

HAMOUNNAVARD S., BAHRAMI A.M., RAZMJOU M., ASADI SAMANI M., HATAMI LAK M.. EVALUATION OF NERIUM OLEANDER AQUEOUS EXTRACT EFFECT ON STAPHYLOCOCCUS AUREUSAND STAPHYLOCOCCUS EPIDERMIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2013;15(1):46-54. Available from: https://sid.ir/paper/58385/en

IEEE: Copy

S. HAMOUNNAVARD, A.M. BAHRAMI, M. RAZMJOU, M. ASADI SAMANI, and M. HATAMI LAK, “EVALUATION OF NERIUM OLEANDER AQUEOUS EXTRACT EFFECT ON STAPHYLOCOCCUS AUREUSAND STAPHYLOCOCCUS EPIDERMIS,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 1, pp. 46–54, 2013, [Online]. Available: https://sid.ir/paper/58385/en

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