PREVALENCE OF PER-1- TYPE EXTENDED-SPECTRUM BETA-LACTAMAES IN CLINICAL STRAINS OFPSEUDOMONAS AERUGINOSA ISOLATED FROM TABRIZ, IRAN

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AKHI MOHAMMAD TAGHI; KHALILI YONES; GHOTTASLOU REZA; AGHAZADEH MOHAMMAD; SEROUSH BAR HAGHI MOHAMMAD HOSEIN; YOUSEFI SABER

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Journal: IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES Year:2012 | Volume:15 | Issue:1 Page(s): 678-682

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Title

PREVALENCE OF PER-1- TYPE EXTENDED-SPECTRUM BETA-LACTAMAES IN CLINICAL STRAINS OFPSEUDOMONAS AERUGINOSA ISOLATED FROM TABRIZ, IRAN

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Keywords

COMBINED DISK TEST

DOUBLE DISK SYNERGY TEST

EXTENDED- SPECTRUM BETA- LACTAMASE

PER- 1GENE

PSEUDOMONAS AERUGINOSA

Abstract

Objective(s): The aim of this study was to investigate the presence of PER-1-type ESBLs in drug resistantPseudomonas aeruginosaisolates.Materials and Methods: During one-year period (2008-2009), following isolation and identification of 56P. aeruginosa, the E -test method was performed for determination of minimal inhibitory concentration of ceftazidim. The isolates that they had MIC ³16 mg/ml against ceftazidim were used for determination of ESBL-producing by combined disk test (CDT) and double disk synergy test (DDST) methods.Bla PER-1 gene was investigated by PCR.P. aeruginosaKOAS was used as positive control.Results: Twenty-nine (51.78%) out of fifty six isolates had MIC³16 mg/ml to ceftazidime, twenty two (75.86%) of them were ESBL producers. Some isolates (27.5%) containedbla PER-1 gene.Conclusion: PER-1-type ESBLs producingP.aeruginosa has not been reported previously in Tabriz but there has been a rather high prevalence of it.

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APA: Copy

AKHI, MOHAMMAD TAGHI, KHALILI, YONES, GHOTTASLOU, REZA, AGHAZADEH, MOHAMMAD, SEROUSH BAR HAGHI, MOHAMMAD HOSEIN, & YOUSEFI, SABER. (2012). PREVALENCE OF PER-1- TYPE EXTENDED-SPECTRUM BETA-LACTAMAES IN CLINICAL STRAINS OFPSEUDOMONAS AERUGINOSA ISOLATED FROM TABRIZ, IRAN. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 15(1), 678-682. SID. https://sid.ir/paper/586557/en

Vancouver: Copy

AKHI MOHAMMAD TAGHI, KHALILI YONES, GHOTTASLOU REZA, AGHAZADEH MOHAMMAD, SEROUSH BAR HAGHI MOHAMMAD HOSEIN, YOUSEFI SABER. PREVALENCE OF PER-1- TYPE EXTENDED-SPECTRUM BETA-LACTAMAES IN CLINICAL STRAINS OFPSEUDOMONAS AERUGINOSA ISOLATED FROM TABRIZ, IRAN. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2012;15(1):678-682. Available from: https://sid.ir/paper/586557/en

IEEE: Copy

MOHAMMAD TAGHI AKHI, YONES KHALILI, REZA GHOTTASLOU, MOHAMMAD AGHAZADEH, MOHAMMAD HOSEIN SEROUSH BAR HAGHI, and SABER YOUSEFI, “PREVALENCE OF PER-1- TYPE EXTENDED-SPECTRUM BETA-LACTAMAES IN CLINICAL STRAINS OFPSEUDOMONAS AERUGINOSA ISOLATED FROM TABRIZ, IRAN,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 15, no. 1, pp. 678–682, 2012, [Online]. Available: https://sid.ir/paper/586557/en

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