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Information Journal Paper

Title

THE EFFECTS OF HYDROALCOHOLIC EXTRACT OF LEAVES AND ONION OF ALLIUM PARADOXUM ON GIARDIA LAMBLIA IN MICE

Pages

  13-22

Abstract

 Background and aims: Giardia is an intestinal protozoan parasite in humans and various mammals. Chemical drugs that are prescribed to treat this disease currently have adverse effects and no proven efficacy. So it seems necessary to find a drug with fewer side effects to treat this parasitic disease. Therefore, the aim of present study was investigated the effects of hydroalcoholic extract of leaves and onion of ALLIUM PARADOXUM on GIARDIA LAMBLIA in Balb/ c mice.Methods: In this experimental study, 2×105 cysts were fed to 50 Balb/ c mice in 10 groups except negative control group. After confirming contamination, they were treated for 3 days with hydroalcoholic extract of leaves and onion of ALLIUM PARADOXUM (doses of 20, 50, 100 mg/ml) and Metronidazole as a controlling drug.Results: According to the results of this study, Costumes onion extract at a dose of 100 mg/ml is capable of removing G. lamblia cysts. This effect is significant compared to the control group (P<0.05). It also became clear that leaves of ALLIUM PARADOXUM have no significant effect on G. lambliaparasite, but it may increase the effect of onion of ALLIUM PARADOXUM. In other words, it has a synergistic effect.Conclusion: Due to good effect of ALLIUM PARADOXUM in in vivo conditions on the parasite G. lambliaand many side effects of drugs which have been reported, it can be introduced as a natural compound against Giardiasis.

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    APA: Copy

    ELMI, TAHER, GHOLAMI, SHIRZAD, AZADBAKHT, MOHAMAD, RAHIMI ESBOEI, BAHMAN, & GERAILI, ZAHRA. (2014). THE EFFECTS OF HYDROALCOHOLIC EXTRACT OF LEAVES AND ONION OF ALLIUM PARADOXUM ON GIARDIA LAMBLIA IN MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 16(5), 13-22. SID. https://sid.ir/paper/58705/en

    Vancouver: Copy

    ELMI TAHER, GHOLAMI SHIRZAD, AZADBAKHT MOHAMAD, RAHIMI ESBOEI BAHMAN, GERAILI ZAHRA. THE EFFECTS OF HYDROALCOHOLIC EXTRACT OF LEAVES AND ONION OF ALLIUM PARADOXUM ON GIARDIA LAMBLIA IN MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;16(5):13-22. Available from: https://sid.ir/paper/58705/en

    IEEE: Copy

    TAHER ELMI, SHIRZAD GHOLAMI, MOHAMAD AZADBAKHT, BAHMAN RAHIMI ESBOEI, and ZAHRA GERAILI, “THE EFFECTS OF HYDROALCOHOLIC EXTRACT OF LEAVES AND ONION OF ALLIUM PARADOXUM ON GIARDIA LAMBLIA IN MICE,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 5, pp. 13–22, 2014, [Online]. Available: https://sid.ir/paper/58705/en

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