IN VITRO ANTIFUNGAL EFFECT OF THYMUS VULGARIS ESSENCE ON CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH ORAL CANDIDIASIS

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ZIA M.A.; BAYAT M.; KHALKHALI H.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2011 | Volume:13 | Issue:3 Page(s): 44-52

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Title

IN VITRO ANTIFUNGAL EFFECT OF THYMUS VULGARIS ESSENCE ON CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH ORAL CANDIDIASIS

Author(s)

ZIA M.A. | BAYAT M. | KHALKHALI H. | Issue Writer Certificate

Keywords

CANDIDA ALBICANSQ3

ORAL CANDIDIASISQ2

THYMUS VULGARIS ESSENCEQ2

Abstract

Background and aims: CANDIDA ALBICANS is the most common etiologic agent of diseases caused by yeasts of Candida genus. The treatment of these infections is necessary because they may spread in neutropenic and immunosuppressed patients. Fungi resistance to some antifungal drugs is being increased. In addition, many of these drugs are toxic and expensive. Therefore, the study of natural plant products which can be effective against these fungi is necessary. Among the plants which have shown in vitro efficient biologic activity, is Thymus vulgaris. Thus the aim of this research was to study the inhibitory effect of THYMUS VULGARIS ESSENCE on of CANDIDA ALBICANS growth.Methods: In this research, fifty patients with ORAL CANDIDIASIS were studied. The obtained swab samples were cultured on Sabouraud Dextrose Agar supplemented with cycloheximide and chloramphenicol (SCC) medium, finally with performance of supplementary tests.32 isolates were recognized as CANDIDA ALBICANS. Then we added THYMUS VULGARIS ESSENCE to SCC medium in different concentrations and the Minimum Inhibitory Concentration (MIC) of the essence was accounted for different suspension dilutions of CANDIDA ALBICANS.Results: The MIC of the THYMUS VULGARIS ESSENCE for the dilutions of 100, 10-1 and 10-2 of CANDIDA ALBICANS was 0.390 ml/medium and for dilutions of 10-3 and 10-4 were 0.195 and 0.0975 ml/ medium.Conclusion: The THYMUS VULGARIS ESSENCE has a very good antifungal effect against CANDIDA ALBICANS so that low amounts it can inhibit CANDIDA ALBICANS growth.

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APA: Copy

ZIA, M.A., BAYAT, M., & KHALKHALI, H.. (2011). IN VITRO ANTIFUNGAL EFFECT OF THYMUS VULGARIS ESSENCE ON CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH ORAL CANDIDIASIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 13(3), 44-52. SID. https://sid.ir/paper/58830/en

Vancouver: Copy

ZIA M.A., BAYAT M., KHALKHALI H.. IN VITRO ANTIFUNGAL EFFECT OF THYMUS VULGARIS ESSENCE ON CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH ORAL CANDIDIASIS. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;13(3):44-52. Available from: https://sid.ir/paper/58830/en

IEEE: Copy

M.A. ZIA, M. BAYAT, and H. KHALKHALI, “IN VITRO ANTIFUNGAL EFFECT OF THYMUS VULGARIS ESSENCE ON CANDIDA ALBICANS ISOLATED FROM PATIENTS WITH ORAL CANDIDIASIS,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 13, no. 3, pp. 44–52, 2011, [Online]. Available: https://sid.ir/paper/58830/en

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