REDUCTION OF COLONIZATION OF ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) IN MICE BY PRO BIOTIC (LACTOBACILLUS CASEI)

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FAZELI A.; GHASEMIAN SAFAEI H.; MIRNEJAD R.

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Journal: Journal of Shahrekord University of Medical Sciences Year:2004 | Volume:6 | Issue:1 Page(s): 26-33

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Information Journal Paper

Title

REDUCTION OF COLONIZATION OF ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) IN MICE BY PRO BIOTIC (LACTOBACILLUS CASEI)

Author(s)

FAZELI A. | GHASEMIAN SAFAEI H. | MIRNEJAD R. | Issue Writer Certificate

Keywords

BALB/C MOUSEQ4

ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC)Q4

LACTOBACILLUS CASEIQ2

PROBIOTICQ2

TRAVELERS DIARRHEAQ2

Abstract

Background and Aim: Diarrhea still is one of the major health problems in many parts of the world. In developing countries Enterotoxigenic Escherichia coli (ETEC) is a major cause of severe disease in children and it is the most frequent cause of traveler's diarrhea. Diarrhea caused by ETEC is dependent on its colonization in the small intestine, thus reducing its colonization can potentially reduce the disease. PROBIOTICs are microorganisms (bacteria and yeasts) that have beneficial effects on the health of the host when ingested. The purpose of this study was to use the LACTOBACILLUS CASEI as a PROBIOTIC organism for reducing the shedding and colonization of ETEC in the BALB/C MOUSE intestine.Method: The mice allocated into either a PROBIOTIC-treatedgroup or a control group. The treated group were given PROBIOTIC (1x 108 cfu) for either 3 or 6 days, and the control group were not given any PROBIOTIC.Seventy-two hours after the last oral administration of PROBIOTIC, the test and control mice were challenged with ETEC (1 x 108 cfu). Frequency of shedding was evaluated by colony counting of fecal samples.Results: The results indicated that mice given PROBIOTIC for 3 or 6 days had a significant reduction in the trequency of ETEC shedding (p<0.00l) compared to the control group.Conclusion: The findings suggests the LACTOBACILLUS CASEI as a possible candidate for a PROBIOTIC against Enterotoxigenic Escherichia coli.

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APA: Copy

FAZELI, A., GHASEMIAN SAFAEI, H., & MIRNEJAD, R.. (2004). REDUCTION OF COLONIZATION OF ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) IN MICE BY PRO BIOTIC (LACTOBACILLUS CASEI). JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 6(1), 26-33. SID. https://sid.ir/paper/58920/en

Vancouver: Copy

FAZELI A., GHASEMIAN SAFAEI H., MIRNEJAD R.. REDUCTION OF COLONIZATION OF ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) IN MICE BY PRO BIOTIC (LACTOBACILLUS CASEI). JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;6(1):26-33. Available from: https://sid.ir/paper/58920/en

IEEE: Copy

A. FAZELI, H. GHASEMIAN SAFAEI, and R. MIRNEJAD, “REDUCTION OF COLONIZATION OF ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) IN MICE BY PRO BIOTIC (LACTOBACILLUS CASEI),” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 6, no. 1, pp. 26–33, 2004, [Online]. Available: https://sid.ir/paper/58920/en

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