ASSESSMENT OF FEBRILE NEONATES ACCORDING TO LOW RISK CRITERIA FOR SERIOUS BACTERIAL INFECTION

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ZARKESH MARJANEH; HASHEMIAN HOUMAN; MOMTAZBAKHSH MOHAMMAD; ROSTAMI TAHEREH

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Journal: Iranian Journal of Pediatrics Year:2011 | Volume:21 | Issue:4 Page(s): 436-440

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Title

ASSESSMENT OF FEBRILE NEONATES ACCORDING TO LOW RISK CRITERIA FOR SERIOUS BACTERIAL INFECTION

Author(s)

ZARKESH MARJANEH | HASHEMIAN HOUMAN | MOMTAZBAKHSH MOHAMMAD | ROSTAMI TAHEREH | Issue Writer Certificate

Keywords

LOW-RISK CRITERIA

NEONATE

SERIOUS BACTERIAL INFECTION

Abstract

Objective: It is propounded that febrile NEONATEs with low risk criteria (LRC) can be carefully observed without parenteral antimicrobial therapy; but yet, reliability of LRC to exclude SERIOUS BACTERIAL INFECTION (SBI) is uncertain.Methods: T he records of all febrile term NEONATEs, seen in the emergency room and admitted in neonatal ward of 17 Shahrivar children's hospital of Rasht, Iran from January 2004 to January 2009 were reviewed. All of them underwent full sepsis workup. The prevalence of SBI in total population and LRC positive and negative NEONATEs were calculated Findings: A total of 202 records of previously healthy febrile NEONATEs were evaluated. SBI was shown in 38 (18.8%). The most common type of SBI was urinary tract infection (UTI). Sixty-two (31%) NEONATEs had LRC, and only one (1.6%) had SBI (UTI with E. coli). SBI was significantly more common in NEONATEs without LRC (26.6% versus 1.6%, P<0.001). The negative predictive value (NPV) of LRC to exclude SBI was 98.4% (95%confidence interval: 96.7% to 100%).Conclusion: These findings suggest that LRC may be relied upon to exclude SBI in febrile NEONATEs. We propose that all febrile NEONATEs be admitted, ill or LRC negative NEONATEs should undergo a full sepsis work up and be administered systemic antibiotics immediately. LRC positive NEONATEs should be under close observation.

Cites

DIAGNOSTIC VALUE OF IL-6, CRP, WBC, AND ABSOLUTE NEUTROPHIL COUNT TO PREDICT SERIOUS BACTERIAL INFECTION IN FEBRILE INFANTS

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APA: Copy

ZARKESH, MARJANEH, HASHEMIAN, HOUMAN, MOMTAZBAKHSH, MOHAMMAD, & ROSTAMI, TAHEREH. (2011). ASSESSMENT OF FEBRILE NEONATES ACCORDING TO LOW RISK CRITERIA FOR SERIOUS BACTERIAL INFECTION. IRANIAN JOURNAL OF PEDIATRICS, 21(4), 436-440. SID. https://sid.ir/paper/596093/en

Vancouver: Copy

ZARKESH MARJANEH, HASHEMIAN HOUMAN, MOMTAZBAKHSH MOHAMMAD, ROSTAMI TAHEREH. ASSESSMENT OF FEBRILE NEONATES ACCORDING TO LOW RISK CRITERIA FOR SERIOUS BACTERIAL INFECTION. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2011;21(4):436-440. Available from: https://sid.ir/paper/596093/en

IEEE: Copy

MARJANEH ZARKESH, HOUMAN HASHEMIAN, MOHAMMAD MOMTAZBAKHSH, and TAHEREH ROSTAMI, “ASSESSMENT OF FEBRILE NEONATES ACCORDING TO LOW RISK CRITERIA FOR SERIOUS BACTERIAL INFECTION,” IRANIAN JOURNAL OF PEDIATRICS, vol. 21, no. 4, pp. 436–440, 2011, [Online]. Available: https://sid.ir/paper/596093/en

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