Organophosphate compounds and their biodegradation; using enzymes as an increased efficiency approach

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BADRI TALEB; LATIFI ALI MOHAMMAD; HASSANPOUR KAZEM; TAHERI RAMEZAN ALI; MIRZAEI MORTEZA; FARNOOSH GHOLAMREZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MILITARY MEDICINE Year:2019 | Volume:21 | Issue:5 Page(s): 468-478

Download Full-Text

Persian Verion

View:

1,582

Download:

Cites:

Information Journal Paper

Title

Organophosphate compounds and their biodegradation; using enzymes as an increased efficiency approach

Author(s)

Keywords

BiodegradationQ1

AcetylcholinesteraseQ1

Organophosphorus CompoundsQ2

Nervous Chemical AgentsQ1

Degradation EnzymesQ1

Abstract

Organophosphorus Compounds are widely used in pesticides, insecticides in agriculture and as Nervous Chemical Agents. These chemicals inhibit the Acetylcholinesterase enzyme activity that is responsible for the nervous impulse in organisms. This effect leads to an increase in acetylcholine level and finally neuronal complications. Many methods are used to degrade and decontaminate these compounds, such as: the use of chemicals, burial of toxins, burning and Biodegradation. The chemical and physical methods are often toxic, allergic, corrosive and nonspecific and harmful for the environment and are not usable in war spaces. Biodegradation is an effective and safe method that is performed under controlled conditions for the decomposition of various constituents, including Organophosphorus Compounds, by biological agents. Biodegradation is performed using microbes to detoxify and decompose contaminants. These strains contain broad substrate-degrading enzymes. Although the use of natural strains as vital catalysts is an interesting method for the treatment of Organophosphorus Compounds, the inability of Organophosphorus Compounds to cross the membrane width reduces the total catalytic power, so the use of recombinant enzymes for the decomposition of Organophosphorus Compounds can be of great help in removing contaminants, especially in war environments. Many enzymes have been identified and used for this purpose, but most notably include: Diisopropyl-fluorophosphatase (DFPasae), Organophosphorus acid anhydrolase (OPAA) and Organophosphorus Hydrolase (OPH). In this review, in addition to describing the Organophosphorus Compounds and their effects, Biodegradation especially by use of enzymes was considered. The understanding and mastering of this knowledge could help researchers in the use of chemical degrading enzymes, especially organophosphates, in spray and enzymatic ointments in military environments.

Cites

No record.

References

No record.

Cite

APA: Copy

BADRI, TALEB, LATIFI, ALI MOHAMMAD, HASSANPOUR, KAZEM, TAHERI, RAMEZAN ALI, MIRZAEI, MORTEZA, & FARNOOSH, GHOLAMREZA. (2019). Organophosphate compounds and their biodegradation; using enzymes as an increased efficiency approach. JOURNAL OF MILITARY MEDICINE, 21(5 ), 468-478. SID. https://sid.ir/paper/61739/en

Vancouver: Copy

BADRI TALEB, LATIFI ALI MOHAMMAD, HASSANPOUR KAZEM, TAHERI RAMEZAN ALI, MIRZAEI MORTEZA, FARNOOSH GHOLAMREZA. Organophosphate compounds and their biodegradation; using enzymes as an increased efficiency approach. JOURNAL OF MILITARY MEDICINE[Internet]. 2019;21(5 ):468-478. Available from: https://sid.ir/paper/61739/en

IEEE: Copy

TALEB BADRI, ALI MOHAMMAD LATIFI, KAZEM HASSANPOUR, RAMEZAN ALI TAHERI, MORTEZA MIRZAEI, and GHOLAMREZA FARNOOSH, “Organophosphate compounds and their biodegradation; using enzymes as an increased efficiency approach,” JOURNAL OF MILITARY MEDICINE, vol. 21, no. 5 , pp. 468–478, 2019, [Online]. Available: https://sid.ir/paper/61739/en

Related Journal Papers