TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID

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YAN YA MIN; FAN QIAO LING; LI AI QIU; CHEN JIA LING; DONG FEI FEI; GONG MEI

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Title

TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID

Author(s)

Keywords

TREATMENT

DRUG EXTRAVASATION

HYALURONIDASE

HIRUDOID

NEONATE

Abstract

Objective: To analyze the effects of HYALURONIDASE and HIRUDOID TREATMENT on DRUG EXTRAVASATION in NEONATEs.Methods: The medical records of 13 NEONATEs with DRUG EXTRAVASATION treated with HYALURONIDASE and HIRUDOID between August 1st, 2010 and May 1st, 2012 were analyzed retrospectively. The TREATMENT procedure for DRUG EXTRAVASATION adhered to the protocol in neonatal department. The information including age, sex, weight, diagnosis, size of affected area, site of extravasation and TREATMENT was collected.Findings: The extravasation injuries alleviated and the symptoms improved after TREATMENT, no adverse drug effects were reported with use of HYALURONIDASE and HIRUDOID.Conclusion: The TREATMENT appeared to be beneficial in the management of extravasations of various medications in NEONATEs and may be useful in reducing the severity of cutaneous toxicosis. However, further studies with large samples are still needed to assess the effectiveness and safety of HYALURONIDASE and HIRUDOID.

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APA: Copy

YAN, YA MIN, FAN, QIAO LING, LI, AI QIU, CHEN, JIA LING, DONG, FEI FEI, & GONG, MEI. (2014). TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID. IRANIAN JOURNAL OF PEDIATRICS, 24(4), 352-358. SID. https://sid.ir/paper/630367/en

Vancouver: Copy

YAN YA MIN, FAN QIAO LING, LI AI QIU, CHEN JIA LING, DONG FEI FEI, GONG MEI. TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2014;24(4):352-358. Available from: https://sid.ir/paper/630367/en

IEEE: Copy

YA MIN YAN, QIAO LING FAN, AI QIU LI, JIA LING CHEN, FEI FEI DONG, and MEI GONG, “TREATMENT OF CUTANEOUS INJURIES OF NEONATES INDUCED BY DRUG EXTRAVASATION WITH HYALURONIDASE AND HIRUDOID,” IRANIAN JOURNAL OF PEDIATRICS, vol. 24, no. 4, pp. 352–358, 2014, [Online]. Available: https://sid.ir/paper/630367/en

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