EVALUATION OF THE POST OPERATIVE ANALGESIC EFFECT OF LIDOCAINE WITH NEOSTIGMINE COMPARED WITH LIDOCAINE ALONE IN PEDIATRIC CAUDAL ANESTHESIA

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AFSHAR M.; SADEGHI A.; DABAGH ALI

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2003 | Volume:22 | Issue:40 Page(s): 59-68

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Title

EVALUATION OF THE POST OPERATIVE ANALGESIC EFFECT OF LIDOCAINE WITH NEOSTIGMINE COMPARED WITH LIDOCAINE ALONE IN PEDIATRIC CAUDAL ANESTHESIA

Author(s)

AFSHAR M. | SADEGHI A. | DABAGH ALI | Issue Writer Certificate

Keywords

ANESTHESIAQ4

ACUTE POST-OPERATIVE PAINQ4

CAUDAL ANESTHESIAQ4

NEOSTIGMINEQ4

Abstract

Adjuvant drugs have been proposed to the accompanied with local anesthetic drugs to increase their analgesic efficacy. In this study, NEOSTIGMINE has been added to lidocaine to assess its additive analgestic effects in caudal ANESTHESIA.In a double blind descriptive analytical clinical trial, 60 patients aged 2 to 8 years and in ASA class I were allocated randomly in the case and control groups. All the patients had lower abdominal operations and were anesthetized generally with 1μg/kg fentanyl, 5mg/kg sodium thiopental, 66% N2O, 34% O2 and 1 MAC halothane. The patients had spontaneous ventilation after completion of the surgery, the case group received a caudal block with 0.5% lidocaine (1cc/kg) plus NEOSTIGMINE (20μg/kg) and a total volume of caudally administered drug of 1cc/kg. The control group received the same dose and volume of lidocaine without NEOSTIGMINE. Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) was used as the pain assessment scale, in the 1st, 3th, 6th and 24th hours after the surgery. Student t-test and chi-square tests were used for data analysis. SPSS software (version 10) was used for data entry and analysis.The two groups were similar regarding demographic variables. Pain scores were lower in the case group in the 3th, 6th and 24th hours after the surgery (a significant statistical difference); while the control group had lower pain scores at the first hour post-operatively. None of the patients in the 2 groups needed post-operative analgesics. Also, no post-operative complication was encountered.This study suggests that NEOSTIGMINE could be an effective adjuvant for lidocaine in caudal ANESTHESIA for pediatric patients compared with lidocaine administered lonely.Complementary studies are suggested to determine the best dosage of NEOSTIGMINE.

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APA: Copy

AFSHAR, M., SADEGHI, A., & DABAGH, ALI. (2003). EVALUATION OF THE POST OPERATIVE ANALGESIC EFFECT OF LIDOCAINE WITH NEOSTIGMINE COMPARED WITH LIDOCAINE ALONE IN PEDIATRIC CAUDAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 22(40), 59-68. SID. https://sid.ir/paper/63219/en

Vancouver: Copy

AFSHAR M., SADEGHI A., DABAGH ALI. EVALUATION OF THE POST OPERATIVE ANALGESIC EFFECT OF LIDOCAINE WITH NEOSTIGMINE COMPARED WITH LIDOCAINE ALONE IN PEDIATRIC CAUDAL ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2003;22(40):59-68. Available from: https://sid.ir/paper/63219/en

IEEE: Copy

M. AFSHAR, A. SADEGHI, and ALI DABAGH, “EVALUATION OF THE POST OPERATIVE ANALGESIC EFFECT OF LIDOCAINE WITH NEOSTIGMINE COMPARED WITH LIDOCAINE ALONE IN PEDIATRIC CAUDAL ANESTHESIA,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 22, no. 40, pp. 59–68, 2003, [Online]. Available: https://sid.ir/paper/63219/en

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