COMPARISON OF BIS-GUIDED TARGET-CONTROLLED INFUSION VERSUS MANUALLY CONTROLLED INFUSION IN TYMPANOMASTOI-DECTOMY SURGERIES

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YEGANEH N.; ROSHANI B.; YARI M.

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Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2007 | Volume:29 | Issue:59 Page(s): 24-36

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Title

COMPARISON OF BIS-GUIDED TARGET-CONTROLLED INFUSION VERSUS MANUALLY CONTROLLED INFUSION IN TYMPANOMASTOI-DECTOMY SURGERIES

Author(s)

YEGANEH N. | ROSHANI B. | YARI M. | Issue Writer Certificate

Keywords

TOTAL INTRAVENOUS ANESTHESIAQ3

TARGET-CONTROLLED INFUSIONQ3

PROPOFOLQ3

REMIFENTANIQ3

BISQ3

Abstract

Background: Target-controlled intravenous infusion (TCI) is a new delivery system of anesthetic drugs. The rational of TCI is based on the obtaining and control of a desired target concevtration in plasma or effect-site (biophase). Shuttler avd Col first described the use of TCI system in 1983. The technique allows obtaining more precise titration of anesthetic drug, proceeding by successive stages of concentration of anesthetic drugs. TCI provides better adjustment between concentrations of the anesthtic drug and clinically required effects, that is a major interest in anesthesia practice, particularly for induction and the predict the recovery of patients. In this study we compared the efficacy of TCI and more traditional manually controlled infusion (MCI) in tympanomastoidectomy surgeries in Kermanshah Imam Khomeini Hospital.Materials and Methods: 60 ASA I-II patients who were candidates for tympanomastoid surgeries enrolled in this clinical trial study after written inform consent. Exclusion criteria were any regular use or addiction to opium derivatives or sedatives, also any use of medication affecting the sympathic system excluded the case from entering to study. All of the cases were monitored by BIS and were unpremedicated. The data were analysed by independent t-test, leven and U Mann-Whitney. for analysis of qualitative variables X2 and exact fischer test were used. Meaningful level of all of the tests was 0.05%.Results: Infusion rate of PROPOFOL and REMIFENTANIl were lower in TCI group patients. There wasn't any significant difference of wake up time between two groups but patients discharged faster from recovery to the ward in TCI group patients (Aldrete score). The patients in TCI group showed more hemodynamic stability during induction and maintenance anesthesia. Costs of drugs used in anesthesia were more in MCI group patients and finally post operative nausea and vomiting incidence was lower in TCI group patients.Conclusion: Efficacy of TCI with PROPOFOL and REMIFENTANIl is better than manually controlled infusion especially in the selection of patients and plasmatic drug target is good.

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APA: Copy

YEGANEH, N., ROSHANI, B., & YARI, M.. (2007). COMPARISON OF BIS-GUIDED TARGET-CONTROLLED INFUSION VERSUS MANUALLY CONTROLLED INFUSION IN TYMPANOMASTOI-DECTOMY SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 29(59), 24-36. SID. https://sid.ir/paper/63306/en

Vancouver: Copy

YEGANEH N., ROSHANI B., YARI M.. COMPARISON OF BIS-GUIDED TARGET-CONTROLLED INFUSION VERSUS MANUALLY CONTROLLED INFUSION IN TYMPANOMASTOI-DECTOMY SURGERIES. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2007;29(59):24-36. Available from: https://sid.ir/paper/63306/en

IEEE: Copy

N. YEGANEH, B. ROSHANI, and M. YARI, “COMPARISON OF BIS-GUIDED TARGET-CONTROLLED INFUSION VERSUS MANUALLY CONTROLLED INFUSION IN TYMPANOMASTOI-DECTOMY SURGERIES,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 29, no. 59, pp. 24–36, 2007, [Online]. Available: https://sid.ir/paper/63306/en

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