SERUM LEVELS OF NITRIC OXIDE IN SLOW CORONARY FLOW PHENOMENON

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NEMATI MOHADESEH; RASMI YOUSEF; KHADEM ANSARI MOHAMMAD HASSAN; Faramarz Gaznagh Sanaz; SEYED MOHAMMADZAD MIR HOSSEIN; Mokarizadeh Narmin; KHERADMAND FATEMEH

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Title

SERUM LEVELS OF NITRIC OXIDE IN SLOW CORONARY FLOW PHENOMENON

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Keywords

CORONARY SLOW FLOWQ1

NITRIC OXIDEQ3

ENDOTHELIAL DYSFUNCTIONQ1

ANGIOGRAPHYQ1

Abstract

Background & Aims: CORONARY SLOW FLOW phenomenon (SCF) is normal or near-normal angiographically that is known with delayed passage of contrast in coronary arteries. Etiology of SCF is unknown. ENDOTHELIAL DYSFUNCTION is one of the main factors in the etiology of SCF and vascular endothelium-derived NITRIC OXIDE is one of the main biochemical factors in the regulation of vascular tonisity. The aim of this study was to evaluate serum levels of NITRIC OXIDE metabolites in SCF patients.Materials and Methods: Thirty patients with SCF (53±11.83 years) and 30 healthy controls (51.37±11.89 years) were entered in the case-control investigation. Cases and controls were matched for age, gender, and body mass index. Three ml of blood samples were collected in tubes. Serum concentrations of NO metabolites were measured by ELISA method (Ltd. Co, China).Results: The mean values of NITRIC OXIDE metabolites in controls and patients with SCF was 18.04 ±7.99 and 17.93±4.31mmol/L, respectively; P=0.129.Conclusion: ENDOTHELIAL DYSFUNCTION is the main factor in the pathogenesis of SCF. But in this study, serum levels of NITRIC OXIDE metabolites were not statistically significant in patients with SCF patients versus controls. So it was recommended to further investigate with more subjects.

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APA: Copy

NEMATI, MOHADESEH, RASMI, YOUSEF, KHADEM ANSARI, MOHAMMAD HASSAN, Faramarz Gaznagh, Sanaz, SEYED MOHAMMADZAD, MIR HOSSEIN, Mokarizadeh, Narmin, & KHERADMAND, FATEMEH. (2016). SERUM LEVELS OF NITRIC OXIDE IN SLOW CORONARY FLOW PHENOMENON. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 27(3), 215-221. SID. https://sid.ir/paper/63979/en

Vancouver: Copy

NEMATI MOHADESEH, RASMI YOUSEF, KHADEM ANSARI MOHAMMAD HASSAN, Faramarz Gaznagh Sanaz, SEYED MOHAMMADZAD MIR HOSSEIN, Mokarizadeh Narmin, KHERADMAND FATEMEH. SERUM LEVELS OF NITRIC OXIDE IN SLOW CORONARY FLOW PHENOMENON. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2016;27(3):215-221. Available from: https://sid.ir/paper/63979/en

IEEE: Copy

MOHADESEH NEMATI, YOUSEF RASMI, MOHAMMAD HASSAN KHADEM ANSARI, Sanaz Faramarz Gaznagh, MIR HOSSEIN SEYED MOHAMMADZAD, Narmin Mokarizadeh, and FATEMEH KHERADMAND, “SERUM LEVELS OF NITRIC OXIDE IN SLOW CORONARY FLOW PHENOMENON,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 27, no. 3, pp. 215–221, 2016, [Online]. Available: https://sid.ir/paper/63979/en

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