EVALUATION OF THE EFFECT OF ALLIUM SATIVUM AQUEOUS EXTRACT ON SERUM NITRIC OXIDE IN MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOAIEDMOHSENI SAKINE; ROHANI HAMIDEH; EGHTEDARDOOST MARZIEH; EMADI SEYED MOHAMMADREZA; ROGHANI MEHRDAD; GHAZANFARI TOOBA

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DANESHVAR MEDICINE Year:2015 | Volume:22 | Issue:115 Page(s): 35-44

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,147

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF THE EFFECT OF ALLIUM SATIVUM AQUEOUS EXTRACT ON SERUM NITRIC OXIDE IN MICE

Author(s)

Keywords

ALLIUM SATIVUMQ3

SERUM NITRIC OXIDEQ2

GRIESS REACTIONQ3

ACETONITRILQ2

BALB/C MICE.Q2

Abstract

Background and Objective: ALLIUM SATIVUM or garlic belongs to Liliaceae family. Garlic has been used in the Iranian Traditional Medicine for treatment of different diseases like infections, cancers, digestion disorders and heart diseases. Nitric oxide (NO) is produced in immunity response and inflammatory conditions. According to immunomodulator effect of garlic, the effect of garlic extract on serum metabolites of NO (nitrite and nitrate) in BALB/C MICE.was studied.Material and Methods: In this experimental study, 30 BALB/C MICE.(female, 6-8 weeks old) were divided into 6 groups (three groups received garlic and three groups as control). Each mouse received 20 mg/kg/day of garlic extract intraperitonealy for one week (mice in control groups received normal saline). Mice were killed at 24 hours, 1st and 2nd weeks after garlic extract treatment. Serum was prepared and nitrite and nitrate were assayed by Greiss method. Meanwhile, t test was used for statistical analysis.Results: Primary nitrite increased by 7.5% and 29% and nitrite+nitrate increased by 42% and 12% in 24 hours and one week after last injection, respectively. Primary nitrite decreased by 2.5% and nitrite+nitrate increased by 4.8% two weeks after last injection. All t-test values were not significant.Conclusion: One week administration of 20 mg/kg of garlic extract increases serum NO metabolites levels time dependently but not significantly and this effect weakens with time.

Cites

No record.

References

Cite

APA: Copy

MOAIEDMOHSENI, SAKINE, ROHANI, HAMIDEH, EGHTEDARDOOST, MARZIEH, EMADI, SEYED MOHAMMADREZA, ROGHANI, MEHRDAD, & GHAZANFARI, TOOBA. (2015). EVALUATION OF THE EFFECT OF ALLIUM SATIVUM AQUEOUS EXTRACT ON SERUM NITRIC OXIDE IN MICE. DANESHVAR MEDICINE, 22(115), 35-44. SID. https://sid.ir/paper/30881/en

Vancouver: Copy

MOAIEDMOHSENI SAKINE, ROHANI HAMIDEH, EGHTEDARDOOST MARZIEH, EMADI SEYED MOHAMMADREZA, ROGHANI MEHRDAD, GHAZANFARI TOOBA. EVALUATION OF THE EFFECT OF ALLIUM SATIVUM AQUEOUS EXTRACT ON SERUM NITRIC OXIDE IN MICE. DANESHVAR MEDICINE[Internet]. 2015;22(115):35-44. Available from: https://sid.ir/paper/30881/en

IEEE: Copy

SAKINE MOAIEDMOHSENI, HAMIDEH ROHANI, MARZIEH EGHTEDARDOOST, SEYED MOHAMMADREZA EMADI, MEHRDAD ROGHANI, and TOOBA GHAZANFARI, “EVALUATION OF THE EFFECT OF ALLIUM SATIVUM AQUEOUS EXTRACT ON SERUM NITRIC OXIDE IN MICE,” DANESHVAR MEDICINE, vol. 22, no. 115, pp. 35–44, 2015, [Online]. Available: https://sid.ir/paper/30881/en

Related Journal Papers