CAUSES OF SPLENOMEGALY AND NEED FOR BONE MARROW ASPIRATION FOR DIAGNOSIS
IN TABRIZ PEDIATRIC MEDICAL CENTER

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SULTANI AHARI H.; GHAFARPOUR SAKHA K.

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Journal: Studies in Medical Sciences Year:2002 | Volume:13 | Issue:2 Page(s): 145-153

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Information Journal Paper

Title

CAUSES OF SPLENOMEGALY AND NEED FOR BONE MARROW ASPIRATION FOR DIAGNOSIS IN TABRIZ PEDIATRIC MEDICAL CENTER

Author(s)

SULTANI AHARI H. | GHAFARPOUR SAKHA K. | Issue Writer Certificate

Keywords

SPLENOMEGALYQ3

BONE MARROE ASPIRATIONQ4

ESRQ4

CYTOPENIAQ4

Abstract

Introduction: SPLENOMEGALY is one of the common and important clinical findings in some of the diseases, careful history, physical examination and necessary laboratory tests can lead to underlying causes of SPLENOMEGALY but in some cases further investigations including marrow aspiration is necessary. This study was done in this respect. Materials & Methods: During one year from July 1999 children who were admitted in Tabriz pediatric medical center with SPLENOMEGALY were studied prospectively. In this study 71 patients had clinical and sonographic SPLENOMEGALY with or without hepatomegaly. Possible laboratory tests and imaging studies were done for diagnosis of these patients but in cases of failure, marrow aspiration was done. Results: 19 patients were diagnosed by laboratory assessment. In rest of cases marrow aspiration was performed, which led to final diagnosis in 38 patients but if was not helpful in remaining cases. The results indicated that when either high ESR, CYTOPENIA or both were present marrow aspiration was necessary to establish the diagnosis. In this study leukmeia was the most common cause of SPLENOMEGALY while visceral leishmaniasis was 2nd in frequenty. Discussion: This study shows that dications for bone marrow aspiration in SPLENOMEGALY includes decrease in at least two element of blood cells which has sensitivity of 91.8% and specificity of 73.3% (p<0.001) and high ESR with bicytopenia has sensitivity of 95.6% and specificity of 44.8% (p<0.001).

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APA: Copy

SULTANI AHARI, H., & GHAFARPOUR SAKHA, K.. (2002). CAUSES OF SPLENOMEGALY AND NEED FOR BONE MARROW ASPIRATION FOR DIAGNOSIS IN TABRIZ PEDIATRIC MEDICAL CENTER. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 13(2), 145-153. SID. https://sid.ir/paper/64230/en

Vancouver: Copy

SULTANI AHARI H., GHAFARPOUR SAKHA K.. CAUSES OF SPLENOMEGALY AND NEED FOR BONE MARROW ASPIRATION FOR DIAGNOSIS IN TABRIZ PEDIATRIC MEDICAL CENTER. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2002;13(2):145-153. Available from: https://sid.ir/paper/64230/en

IEEE: Copy

H. SULTANI AHARI, and K. GHAFARPOUR SAKHA, “CAUSES OF SPLENOMEGALY AND NEED FOR BONE MARROW ASPIRATION FOR DIAGNOSIS IN TABRIZ PEDIATRIC MEDICAL CENTER,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 13, no. 2, pp. 145–153, 2002, [Online]. Available: https://sid.ir/paper/64230/en

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