ASSOCIATION BETWEEN HELICOBACTER PYLORI, CAGA, AND VACA STATUS AND CLINICAL PRESENTATION IN IRANIAN CHILDREN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

RAFEEY MANDANA; GHOTASLOU REZA; MILANI MORTEZA; FAROKHI NIMA; GHOJAZADEH MORTEZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Pediatrics Year:2013 | Volume:23 | Issue:5 Page(s): 551-556

Download Full-Text

View:

398

Download:

151

Cites:

Information Journal Paper

Title

ASSOCIATION BETWEEN HELICOBACTER PYLORI, CAGA, AND VACA STATUS AND CLINICAL PRESENTATION IN IRANIAN CHILDREN

Author(s)

Keywords

HELICOBACTER PYLORI

CAGA PROTEIN

VACA PROTEIN

PEPTIC ULCER

Abstract

Objective: Seroprevalence of H. pylori infection in Iran exceeds 65% of pediatric population. In this study, we intended to find association between the virulence genes (cagA and vacA) and clinical presentations.Methods: H. pylori isolates were achieved from the gastric mucosa of children. In each case, the gastric biopsy specimens were cultured and the organisms identified. Detection of different genotypes was carried out by PCR method.Findings: A total of 106 biopsy specimens were cultured and 33 H. pylori isolates obtained. Among these 33 H. pylori strains 24 (73%) were cagA-positive. Genotypes of vacA s1m2, s1m1, s2m2, and s2m1 were 45.5%, 30.3%, 21.2%, and 3%, respectively. Most female patients were infected with genotype s1m2. The vacA-m1 strains were significantly more common in patients with nodular gastritis. There were no statistical differences between the vacA and cagA genotypes and clinical outcomes.Conclusion: The frequency of cagA genotype was high. In this study, nodular gastritis was a common finding and was rather significantly associated with m1 allele of vacA.

Cites

ERADICATION OF HELICOBACTER PYLORI IN CHILDREN BY TRIPLE THERAPY REGIMENS OF AMOXICILLIN, OMEPRAZOLE, AND CLARITHROMYCIN OR AZITHROMYCIN

References

No record.

Cite

APA: Copy

RAFEEY, MANDANA, GHOTASLOU, REZA, MILANI, MORTEZA, FAROKHI, NIMA, & GHOJAZADEH, MORTEZA. (2013). ASSOCIATION BETWEEN HELICOBACTER PYLORI, CAGA, AND VACA STATUS AND CLINICAL PRESENTATION IN IRANIAN CHILDREN. IRANIAN JOURNAL OF PEDIATRICS, 23(5), 551-556. SID. https://sid.ir/paper/669237/en

Vancouver: Copy

RAFEEY MANDANA, GHOTASLOU REZA, MILANI MORTEZA, FAROKHI NIMA, GHOJAZADEH MORTEZA. ASSOCIATION BETWEEN HELICOBACTER PYLORI, CAGA, AND VACA STATUS AND CLINICAL PRESENTATION IN IRANIAN CHILDREN. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2013;23(5):551-556. Available from: https://sid.ir/paper/669237/en

IEEE: Copy

MANDANA RAFEEY, REZA GHOTASLOU, MORTEZA MILANI, NIMA FAROKHI, and MORTEZA GHOJAZADEH, “ASSOCIATION BETWEEN HELICOBACTER PYLORI, CAGA, AND VACA STATUS AND CLINICAL PRESENTATION IN IRANIAN CHILDREN,” IRANIAN JOURNAL OF PEDIATRICS, vol. 23, no. 5, pp. 551–556, 2013, [Online]. Available: https://sid.ir/paper/669237/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops